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Case Report

Functional and Symptomatic Improvement With Cariprazine in Various Psychiatric Patients: A Case Series

Bibliographic Data

ID15527642
AuthorsTommaso Vannucchi (corresponding author), Costanza Taddeucci, Lorenzo Tatini
Year2022
Volume13
Pages878889-878889
Publication date2022-08-01
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.878889
PMID35978843
OpenAlexW4289261438
LanguageEN
Citations received1
References cited25

Cariprazine is a third-generation antipsychotic medication approved for the treatment of schizophrenia and bipolar disorder, with unique pharmacodynamic and pharmacokinetic properties. In this case series, the functional and symptomatic improvement of three patients who had been diagnosed with different psychiatric disorders and who exhibited various symptoms from psychotic to mood symptoms is described. The first case is about a young male patient with bipolar disorder and cocaine abuse who managed to become abstinent from cariprazine. The second and third cases describe patients with psychosis suffering from positive, cognitive and mood symptoms who were non-adherent to previous medication. In both cases, cariprazine was well-tolerated and effective in alleviating symptoms, thus improving their everyday functioning as well. In the discussion, the associations between symptom domains and the receptor profile of cariprazine are also highlighted, providing an explanation of the observed effects. It is concluded that cariprazine is a good treatment option for patients with symptoms of psychosis and addiction; is well-tolerated without the induction of side effects such as weight gain or sedation; and is appropriate for patients who have problems with adherence

Antipsychotic · Bipolar disorder · Mood · Psychiatry · Psychosis · Schizophrenia (object-oriented programming · Bipolar Disorder and Treatment · Clinical Psychology · Medicine · Neurotransmitter Receptor Influence on Behavior · Psychology · Schizophrenia research and treatment

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Citations per year1
Citation span2026 - 2026 (1)
Highly citedNo

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