A bidirectional Mendelian randomization study about the role of morning plasma cortisol in attention deficit hyperactivity disorder
Bibliographic Data
| ID | 15529191 |
|---|---|
| Authors | Jue Hu (0000-0002-2000-8267, Zhejiang Chinese Medical University), Fangfang Li (0000-0001-7047-6918, Zhejiang Chinese Medical University), Chen Dan-fei (Zhejiang Chinese Medical University), Nuo Chen (0000-0002-1267-1982, Zhejiang Chinese Medical University), Ye Chun-lu (Zhejiang Chinese Medical University), Yu Ke-pin (Zhejiang Chinese Medical University), Jian Chen (0000-0002-9033-4033, Zhejiang Chinese Medical University, corresponding author), Xuan Xiao-bo (Zhejiang Provincial Hospital of TCM, corresponding author) |
| Year | 2023 |
| Volume | 14 |
| Pages | 1148759-1148759 |
| Publication date | 2023-06-14 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2023.1148759 |
| PMID | 37389173 |
| OpenAlex | W4380682365 |
| Language | EN |
| Citations received | 1 |
| References cited | 9 |
The study findings suggest a reverse causal relationship between morning plasma cortisol levels and ADHD, with low cortisol levels associated with ADHD. No genetic evidence was found to support a causal relationship between morning plasma cortisol levels and the risk of ADHD. These results suggest that ADHD may lead to a significant reduction in morning plasma cortisol secretion
Biology · Cortisol awakening response · Genetic variants · Genotype · Hydrocortisone · Mendelian randomization · Morning · Phenotype · Pleiotropy · Psychiatry · Attention Deficit Hyperactivity Disorder · Bipolar Disorder and Treatment · Clinical Psychology · Hormonal Regulation and Hypertension · Medicine · Psychology · Endocrinology · Genetics · Internal Medicine
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
Molecular Genetics of Attention-Deficit/Hyperactivity Disorder
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Interpreting findings from Mendelian randomization using the MR-Egger method
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Attention-deficit/hyperactivity disorder
Mendelian randomization with invalid instruments
‘Mendelian randomization’
Reading Mendelian randomisation studies
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2026 - 2026 (1) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 1 |