Disrupted Sense of Agency as a State Marker of First-Episode Schizophrenia
A Large-Scale Follow-Up Study
Bibliographic Data
| ID | 15529193 |
|---|---|
| Authors | Eva Kozáková (0000-0002-2491-0768, Charles University, corresponding author), Eduard Bakštein (0000-0002-4672-4923, Czech Technical University in Prague), Ondřej Havlíček (0000-0003-3533-8557, National Institute of Mental Health), Ondřej Bečev (0000-0003-2504-431X, National Institute of Mental Health), Pavel Knytl (0000-0002-3209-8415, National Institute of Mental Health), Yuliya Zaytseva (0000-0002-6560-8127, National Institute of Mental Health), Filip Španiel (0000-0003-3479-696X, Charles University) |
| Year | 2020 |
| Volume | 11 |
| Pages | 570570-570570 |
| Publication date | 2020-12-18 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2020.570570 |
| PMID | 33391045 |
| OpenAlex | W3111817098 |
| Language | EN |
| Citations received | 1 |
| References cited | 11 |
Background: Schizophrenia is often characterized by a general disruption of self-processing and self-demarcation. Previous studies have shown that self-monitoring and sense of agency (SoA, i.e., the ability to recognize one's own actions correctly) are altered in schizophrenia patients. However, research findings are inconclusive in regards to how SoA alterations are linked to clinical symptoms and their severity, or cognitive factors. Methods: In a longitudinal study, we examined 161 first-episode schizophrenia patients and 154 controls with a continuous-report SoA task and a control task testing general cognitive/sensorimotor processes. Clinical symptoms were assessed with the Positive and Negative Syndrome Scale (PANSS). Results: In comparison to controls, patients performed worse in terms of recognition of self-produced movements even when controlling for confounding factors. Patients' SoA score correlated with the severity of PANSS-derived "Disorganized" symptoms and with a priori defined symptoms related to self-disturbances. In the follow-up, the changes in the two subscales were significantly associated with the change in SoA performance. Conclusion: We corroborated previous findings of altered SoA already in the early stage of schizophrenia. Decreased ability to recognize self-produced actions was associated with the severity of symptoms in two complementary domains: self-disturbances and disorganization. While the involvement of the former might indicate impairment in self-monitoring, the latter suggests the role of higher cognitive processes such as information updating or cognitive flexibility. The SoA alterations in schizophrenia are associated, at least partially, with the intensity of respective symptoms in a state-dependent manner
Agency (philosophy · Cartography · Geography · Psychiatry · Psychoanalysis · Scale (ratio · Schizophrenia (object-oriented programming · Sense of agency · Social science · Sociology · Mental Health and Psychiatry · Neuroscience · Psychology · Psychosomatic Disorders and Their Treatments · Schizophrenia research and treatment
Defective Recognition of One’s Own Actions in Patients With Schizophrenia
Philosophical conceptions of the self
What Is the Sense of Agency and Why Does it Matter?
Schizophrenia, Consciousness, and the Self
Looking for the agent
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
Weighting models and weighting factors
Beyond the comparator model
Explaining delusions of control
Deficits in Agency in Schizophrenia, and Additional Deficits in Body Image, Body Schema, and Internal Timing, in Passivity Symptoms
The Natural Philosophy of Agency
| Citations per year | 0.25 |
|---|---|
| Citation span | 2022 - 2022 (1) |
| Highly cited | No |