Risk-Conferring Glutamatergic Genes and Brain Glutamate Plus Glutamine in Schizophrenia

Bibliographic Data

ID15529239
AuthorsJuan Bustillo (0000-0001-8730-8152, University of New Mexico, corresponding author), Juan R Bustillo, Veena Patel (0000-0002-8650-9080, Mind Research Network), Thomas Jones (0000-0002-4097-1886), Thomas R Jones (0000-0001-5824-5324, University of New Mexico), Rex E Jung (0000-0003-3718-0597, University of New Mexico), Rex Jung, Nattida Payaknait (University of New Mexico), Clifford Qualls (0000-0002-9110-3181, University of New Mexico), José M Canive (New Mexico VA Health Care System), Jingyu Liu (0000-0002-8310-2242, Mind Research Network), Nora I Perrone‐Bizzozero (0000-0002-7608-1332, University of New Mexico), Nora Irma Perrone-Bizzozero, Vince Calhoun (0000-0001-9058-0747, Mind Research Network), Vince D Calhoun, Jessica A Turner (0000-0003-0076-8434, Mind Research Network), Charles Gasparovic (0000-0002-4433-7815, Mind Research Network)
Year2017
Volume8
Pages79-79
Publication date2017-06-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2017.00079
PMID28659829
OpenAlexW2622355154
LanguageDE
References cited25

Elevations in brain Glx are in part, related to common allelic variants of glutamate-related genes known to increase the risk for schizophrenia. Since the glutamate risk scores did not differ between groups, some other genetic or environmental factors likely interact with the variability in glutamate-related risk SNPs to contribute to an increase in brain Glx early in the illness

Amino acid · Biology · Gene · Genotype · Glutamate receptor · Glutamatergic · Glutamine · Magnetic resonance imaging · Psychiatry · Schizophrenia (object-oriented programming · Single-nucleotide polymorphism · SNP · White matter · Diet and metabolism studies · Medicine · Metabolomics and Mass Spectrometry Studies · Neuroscience and Neuropharmacology Research · Endocrinology · Genetics · Internal Medicine

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