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Improvement in self-reported cognitive functioning but not in rumination following online working memory training in a two-year follow-up study of remitted major depressive disorder

Bibliographic Data

ID15529488
AuthorsEivind Haga Ronold (0000-0002-7081-5147, University of Bergen, corresponding author), Sunniva Brurok Myklebost (0000-0002-9884-3481, University of Bergen), Åsa Hammar (0000-0002-3852-8551, Lund University)
Year2023
Volume14
Pages1163073-1163073
Publication date2023-06-05
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2023.1163073
PMID37342173
OpenAlexW4379473449
LanguageEN
Citations received3
References cited50

Self-reported subjective cognitive difficulties (subjective deficits) and rumination are central residual cognitive symptoms following major depressive disorder (MDD). These are risk factors for more a severe course of illness, and despite the considerable relapse risk of MDD, few interventions target the remitted phase, a high-risk period for developing new episodes. Online distribution of interventions could help close this gap. Computerized working memory training (CWMT) shows promising results, but findings are inconclusive regarding which symptoms improve following this intervention, and its long-term effects. This study reports results from a longitudinal open-label two-year follow-up pilot-study of self-reported cognitive residual symptoms following 25 sessions (40 min), five times a week of a digitally delivered CWMT intervention. Ten of 29 patients remitted from MDD completed two-year follow-up assessment. Significant large improvements in self-reported cognitive functioning on the behavior rating inventory of executive function-adult version appeared after two-years ( d = 0.98), but no significant improvements were found in rumination ( d r = 0.575) and at two-year follow-up ( r = 0.308). Strengths in the study included a comprehensive intervention and long follow-up time. Limitations were small sample and no control group. No significant differences between completers and drop-outs were found, however, attrition effects cannot be ruled out and demand characteristics could influence findings. Results suggested lasting improvements in self-reported cognitive functioning following online CWMT. Controlled studies with larger samples should replicate these promising preliminary findings

Cognition · Developmental psychology · Major depressive disorder · Psychiatry · Psychological intervention · Rating scale · Rumination · Clinical Psychology · Functional Brain Connectivity Studies · Mental Health Research Topics · Psychology · Treatment of Major Depression

  • A Secondary Analysis of Longitudinal Pilot‐Study Data Investigating the Associations Between Health‐Related Quality of Life and Executive Functions in Remitted Major Depressive Disorder and Developments Two‐Years Following Cognitive Training

    Open Access•Eivind Haga Ronold, Silje Klundelien Storfossen et al.•Scandinavian Journal of Psychology•2026

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    Open Access•Hossein Malekizadeh, Omid Saed et al.•Frontiers in Psychiatry•2023

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  • Depression

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  • Goal Management Training and Computerized Cognitive Training in Depression—a 2-Year Follow-Up of a Randomized Controlled Trial

    Open Access•Bjørn Ingulfsvann Hagen, Jan Stubberud•Frontiers in Psychiatry•2021

  • A Longitudinal 5-Year Follow-Up Study of Cognitive Function After First Episode Major Depressive Disorder

    Open Access•Eivind Haga Ronold, Marit Therese Schmid et al.•Frontiers in Psychiatry•2020

  • First-Episode Patients Report Cognitive Difficulties in Executive Functioning 1 Year After Initial Episode of Major Depressive Disorder

    Open Access•Marit Therese Schmid, Marit Schmid et al.•Frontiers in Psychiatry•2021

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Citations per year1
Citation span2023 - 2026 (4)
Highly citedNo

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