Evaluation of serum zonulin and occludin levels in obsessive-compulsive disorder and the effect of major depressive disorder comorbidity
Bibliographic Data
| ID | 15529802 |
|---|---|
| Authors | Sertaç Zengil (Erzurum Regional Training and Research Hospital, corresponding author), Esra Laloğlu (0000-0001-5189-3564, Atatürk University) |
| Year | 2024 |
| Volume | 15 |
| Pages | 1395235-1395235 |
| Publication date | 2024-07-23 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Psychiatry (JOURNAL) |
| Journal identifiers | ISSN: 1664-0640 • E-ISSN: 1664-0640 |
| Publisher | Frontiers Media (PUBLISHER • CH) |
| DOI | 10.3389/fpsyt.2024.1395235 |
| PMID | 39109367 |
| OpenAlex | W4400922830 |
| Language | EN |
| References cited | 41 |
Zonulin and occludin levels in this research were significantly higher in the patients with OCD than in the healthy controls. That elevation was positively correlated with disease duration and severity, and the increase was significantly more pronounced in OCD with MDD comorbidity. These findings point to a possible disorder in the intestinal barrier and blood-brain barrier in OCD patients
Biology · Comorbidity · Depression (economics · Major depressive disorder · Occludin · Psychiatry · Tight junction · Dermatology and Skin Diseases · Hair Growth and Disorders · Medicine · Obsessive-Compulsive Spectrum Disorders · Psychology · Gastroenterology · Internal Medicine
| Highly cited | No |
|---|