Desynchronized white matter function and structure in drug-naive first-episode major depressive disorder patients

Bibliographic Data

ID15530206
AuthorsQinger Guo (Zhejiang University), Jingfeng Duan (0000-0001-7015-0328, Zhejiang University), Shuyang Cai (Zhejiang University), Jiaxi Zhang (0000-0001-6177-8690, Zhejiang Normal University), Tao Chen (0000-0001-9162-4078, Zhejiang University), Hong Yang (0000-0003-1416-0526, Zhejiang University, corresponding author)
Year2023
Volume13
Pages1082052-1082052
Publication date2023-01-11
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2022.1082052
PMID36713909
OpenAlexW4315498115
LanguageEN
References cited68

Our results indicated that WM dysfunction may be associated with the pathophysiological mechanism of depression. Our study also suggested that the functional damage of the WM may precedes the structural damage in first-episode MDD patients. Furthermore, for mental disorders, slow-5 frequency band may be a more sensitive functional indicator for early detection of abnormal spontaneous brain activity in WM

Anxiety · Audiology · Cognition · Diffusion MRI · Drug-naïve · Fasciculus · Fractional anisotropy · Hamd · Magnetic resonance imaging · Major depressive disorder · Nuclear magnetic resonance · Physics · Psychiatry · Radiology · White matter · Advanced MRI Techniques and Applications · Advanced Neuroimaging Techniques and Applications · Functional Brain Connectivity Studies · Medicine · Neuroscience · Psychology · Internal Medicine

Tools

Open DOIOpen Access