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Changes in tryptophan breakdown associated with response to multimodal treatment in depression

Bibliographic Data

ID15530285
AuthorsEva Z Reininghaus (0000-0001-5964-4087, Medical University of Graz), Melanie Lenger (Medical University of Graz), Elena Schönthaler (0000-0002-9645-4503, Medical University of Graz, corresponding author), Frederike T Fellendorf (0000-0001-7215-3848, Medical University of Graz), Tatjana Stross (0000-0002-0442-5319, Medical University of Graz), Markus Schwarz (0000-0001-8895-3743, Ludwig-Maximilians-Universität München), Natalie Moll (Ludwig-Maximilians-Universität München), Bernd Reininghaus (Medical University of Graz), Nina Dalkner (0000-0001-7716-3674, Medical University of Graz)
Year2024
Volume15
Pages1380620-1380620
Publication date2024-06-21
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Psychiatry (JOURNAL)
Journal identifiersISSN: 1664-0640 • E-ISSN: 1664-0640
PublisherFrontiers Media (PUBLISHER • CH)
DOI10.3389/fpsyt.2024.1380620
PMID38974918
OpenAlexW4399900710
LanguageEN
References cited7

The results indicate that some compounds of the KYN pathway metabolites can be altered through multimodal long-term interventions in association with treatment response. Especially the pathway degrading KYN further down to 3-HAA and 3-HK/KYN might be decisive for treatment response in depression

Biology · Depression (economics · Psychiatry · Tryptophan · Bipolar Disorder and Treatment · Clinical Psychology · Medicine · Psychology · Stress Responses and Cortisol · Tryptophan and brain disorders · Biochemistry

  • Major depressive disorder

    Open Access•Christian Otte, Stefan M Gold et al.•Nature Reviews Disease Primers•2016

  • Statistical power analyses using G*Power 3.1

    Open Access•Franz Faul, Edgar Erdfelder et al.•Behavior Research Methods•2009

  • Tryptophan as a Link between Psychopathology and Somatic States

    Sascha Russo, Ido P Kema et al.•Psychosomatic Medicine•2003

  • Depression Phenotype, Inflammation, and the Brain

    Rajeev Krishnadas, Neil A Harrison•Psychosomatic Medicine•2016

  • Sex Specific Changes in Tryptophan Breakdown Over a 6 Week Treatment Period

    Open Access•Eva Z Reininghaus, Nina Dalkner et al.•Frontiers in Psychiatry•2019

Citation velocityhistorical
Highly citedNo

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