Clinical profile of early-onset Alzheimer’s disease in Peru
Case series from a neurological care center
Bibliographic Data
| ID | 15533605 |
|---|---|
| Authors | Sheila Castro‐Suárez (0000-0003-0313-3987, corresponding author), Jonathan Zegarra-Valdivia (0000-0003-0497-5270, Universidad Señor de Sipán), María Meza-Vega (0000-0003-4166-6944, National University of San Marcos), Erik Guevara-Silva (0000-0002-1106-5024) |
| Year | 2025 |
| Volume | 42 |
| Issue | 2 |
| Pages | 196-202 |
| Publication date | 2025-06-18 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Peruana de Medicina Experimental y Salud Pública (JOURNAL) |
| Journal identifiers | ISSN: 1726-4634 • E-ISSN: 1726-4642 |
| Publisher | National Institute of Health of Peru (PUBLISHER • PE) |
| DOI | 10.17843/rpmesp.2025.422.14413 |
| PMID | 40900487 |
| OpenAlex | W4412024219 |
| Language | EN |
Motivation for the study. To describe the clinical characteristics of early-onset Alzheimer's disease (EOAD) and compare them according to gender. This condition is considered a rare disease, whose manifestations are still poorly understood. Main findings. The most common clinical presentation of EOAD is the amnestic variant, which mainly affects episodic memory and executive function and is often accompanied by neuropsychiatric symptoms such as depression and irritability. Women tend to have more impairments in calculus, constructive apraxia, and visuospatial functions than men. Implications for public health. By identifying the clinical characteristics of EOAD, healthcare professionals can recognize patients early on. Furthermore, it is essential to broaden the concept of dementia, avoiding limiting it exclusively to the population over 65 years of age
Cognition · Cognitive impairment · Humanities · Psychiatry · Aging, Health, and Disability · Medicine · Philosophy · Psychology · Pediatrics
| Highly cited | No |
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