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Asociación entre tuberculosis infantil grave e inmunización previa con BCG en un hospital de referencia nacional, Perú 1990-2000

Bibliographic Data

ID15534235
AuthorsFélix Llanos-Tejada (0000-0003-1834-1287, Hospital Nacional Dos de Mayo, corresponding author), Hernán Del Castillo (0000-0002-1405-8663, Instituto Nacional de Salud del Niño)
Year2014
Volume29
Issue1
Publication date2014-01-30
Open AccessYes
TypeARTICLE
VenueRevista Peruana de Medicina Experimental y Salud Pública (JOURNAL)
Journal identifiersISSN: 1726-4634 • E-ISSN: 1726-4642
PublisherNational Institute of Health of Peru (PUBLISHER • PE)
DOI10.17843/rpmesp.2012.291.313
OpenAlexW4254702090
LanguageES

The objective of the study was to determine the association between BCG immunization and severe tuberculosis (TB). We performed a retrospective study, including medical records from patients of the pneumology department at the National Children’s Institute in Peru, between the years 1990-2000. A total of 2106 TB cases were reviewed, from them 259 patients were severe (miliary TB or meningoencephalitic TB). from all, 497 cases did not have history of BCG vaccination, 202 had severe TB and 295 non-severe TB (OR = 0.05, 95% CI = 0.03 to 0.07). In conclusion, children diagnosed with TB and who have been immunized with BCG, has 94% lower risk of developing severe TB, compared to children with TB non-immunized with BCG

BCG vaccine · Medical record · Miliary tuberculosis · Retrospective cohort study · Tuberculosis · Vaccination · Child and Adolescent Health · Immunodeficiency and Autoimmune Disorders · Medicine · Tuberculosis Research and Epidemiology · Immunology · Pediatrics · Surgery

Highly citedNo

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