Efecto inhibitorio in vitro de la ftalocianina de aluminio tetrasulfonada clorada frente a Leishmania (Viannia) peruviana y Leishmania (Viannia) braziliensis
Bibliographic Data
| ID | 15534604 |
|---|---|
| Authors | Kelly Vanesa Izarra-Rojas (National University of San Marcos, corresponding author), Nyshon Rojas-Palomino (0000-0003-1303-3744, Instituto Nacional de Salud), José Luis Gonzáles-Medrano (National University of San Marcos), Gloria Minaya-Gómez (0000-0002-0097-9568, Instituto Nacional de Salud), Alfredo Berrocal-Huallpa (National University of Engineering), Julio Santiago-Contreras (National University of San Marcos), Javier Leon (0000-0001-5865-5374, National University of San Marcos), Jorge León-Quispe |
| Year | 2020 |
| Volume | 37 |
| Issue | 3 |
| Pages | 462-70 |
| Publication date | 2020-09-24 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Peruana de Medicina Experimental y Salud Pública (JOURNAL) |
| Journal identifiers | ISSN: 1726-4634 • E-ISSN: 1726-4642 |
| Publisher | National Institute of Health of Peru (PUBLISHER • PE) |
| DOI | 10.17843/rpmesp.2020.373.4465 |
| PMID | 33295548 |
| OpenAlex | W3091575633 |
| Language | EN |
Photodynamic therapy using AlPcClS4 against Leishmania species showed encouraging results, mainly on Leishmania (V.) peruviana, suggesting a potential use as an alternative or complement to the usual treatment of tegumentary leishmaniasis. However, new trials are still required to determine the selectivity index for the intracellular form of the parasite, and to develop methods to facilitate the efficient entry of the molecule into the host cell and the parasite
Amastigote · Biology · Cutaneous leishmaniasis · IC50 · In vitro · Intracellular · Leishmania · Leishmania braziliensis · Leishmaniasis · Parasite hosting · Research on Leishmaniasis Studies · Biochemistry · Immunology · Microbiology · Molecular Biology
| Citation velocity | historical |
|---|---|
| Highly cited | No |