Frecuencia de resistencia a la colistina en Pseudomonas aeruginosa
Primer reporte en el Perú
Bibliographic Data
| ID | 15534631 |
|---|---|
| Authors | Marjhory Zarate (0000-0003-0002-3408, Universidad Peruana Cayetano Heredia, corresponding author), Delsy Barrantes Salinas (0000-0003-2262-401X, Universidad Peruana Cayetano Heredia), Diego Cuicapuza (0000-0002-5735-4614, Universidad Peruana Cayetano Heredia), Jorge Velásquez (0000-0002-0979-2177), Nathaly Fernández (0000-0001-5448-0933), Guillermo Salvatierra (0000-0002-6887-2599, Universidad Peruana Cayetano Heredia), Jesús Tamariz (0000-0002-0827-8117, Universidad Peruana Cayetano Heredia) |
| Year | 2021 |
| Volume | 38 |
| Issue | 2 |
| Pages | 308-12 |
| Publication date | 2021-05-26 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Peruana de Medicina Experimental y Salud Pública (JOURNAL) |
| Journal identifiers | ISSN: 1726-4634 • E-ISSN: 1726-4642 |
| Publisher | National Institute of Health of Peru (PUBLISHER • PE) |
| DOI | 10.17843/rpmesp.2021.382.6977 |
| PMID | 34468581 |
| OpenAlex | W3174552781 |
| Language | ES |
This study aimed to determine the frequency of colistin resistance in Pseudomonas aeruginosa isolates obtained from three healthcare facilities in Lima and cryopreserved at the Laboratorio de Resistencia Antimicrobianos e Inmunopatología of the Universidad Peruana Cayetano Heredia (UPCH). The colistin broth disk elution method was used for the phenotypic identification of colistin resistance. We detected the expression of the mcr-1 gene by using the phenotypic diffusion method with combined colistin and ethylenediaminetetraacetic acid (EDTA) disks; and polymerase chain reaction (PCR) was used for molecular identification of the gene. Of the 97 isolates, 7 (7.2%) were resistant to colistin; however, none carried the mcr-1 gene. This is the first report from Peru on clinical isolates of colistin-resistant Pseudomonas aeruginosa, which suggests the need for implementation of appropriate methodologies for the epidemiological surveillance of colistin-resistant pathogens
Biology · Humanities · Antibiotic Resistance in Bacteria · Antibiotic Use and Resistance · Philosophy · Molecular Biology
| Highly cited | No |
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