Chronic Occlusive Diseases of Lower Limb Arteries in the North (Literature Review)

Chronic occlusive disease of lower limb arteries is a widespread disease of the blood vessels, where due to arteriostenosis there appears arterial misperfusion in the limb. According to the data, nowadays from 2 to 15 % of the adult population suffer from this disease. The literature review shows the relevance of studying the problem of peripheral arteries occlusive diseases (PAD) in the extreme environmental conditions of the Northern latitudes. The analysis conducted by scientists of Surgut city showed that the most important etiological factors resulting in PAD are atherosclerosis (54.5 %) and occlusive tromboangitis (45.3%). Occlusive diseases of the vascular system have multisegmental nature and appear at a young age and often have malignancy flow. The development of atherosclerotic process in its classic version starts at the age of 40-50 years, more often with sectoral lesions in the iliac segment. Occlusive process, once appeared, has no tendency to reverse development, and the outcome of this process (40 % of patients with PAD) is a disability or limb amputation. The study results showed that in young people living in KHMAO-Yugra, endothelial function was characterized by more evident disorders compared to normal rates; the severity of dysfunction was higher than in healthy individuals with risk factors for cardiovascular diseases. The biological age of the subjects met people over 40, and in men, the processes of biological aging was characterized by greater severity

Amputation · Arterial disease · Cardiology · Disease · Etiology · Lower limb · Malignancy · Occlusive · Occlusive arterial disease · Population · Vascular disease · Cerebrovascular and Carotid Artery Diseases · Medicine · Pain Management and Treatment · Peripheral Artery Disease Management · Internal Medicine · Surgery