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Associations Between Body Composition and Metabolic Health in Children With Obesity

Bibliographic Data

ID15536620
AuthorsDesirée López-González (0000-0002-2299-1576, Hospital Infantil de México Federico Gómez), Patricia Clark (0000-0001-7981-5357, Hospital Infantil de México Federico Gómez), Nayely Garibay-Nieto (0000-0001-8261-939X, Hospital General de México), Nayely Garibay‐Nieto (Hospital General de México Eduardo Liceaga Mexico City Mexico), Pamela Reyes-Delpech (Hospital Infantil de México Federico Gómez), Pamela Reyes‐Delpech (Clinical Epidemiology Research Unit Hospital Infantil de México Federico Gómez Mexico City Mexico), Rodolfo Pérez (Hospital Infantil de México Federico Gómez), América Liliana Miranda‐Lora (0000-0002-7848-1890, Hospital Infantil de México Federico Gómez, corresponding author), America Miranda‐Lora (Unit of Epidemiological Research in Endocrinology and Nutrition. Hospital Infantil de México Federico Gómez Mexico City Mexico)
Year2025
Pagese70125-e70125
Publication date2025-12-15
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueMaternal and Child Nutrition (JOURNAL)
Journal identifiersISSN: 1740-8695 • E-ISSN: 1740-8709
PublisherWiley (PUBLISHER • GB)
DOI10.1111/mcn.70125
PMID41396795
OpenAlexW4417427776
LanguageEN
References cited48

Childhood obesity is an increasing public health problem with heterogeneous metabolic health outcomes. In children, distinguishing differences in body composition between individuals with metabolically healthy obesity (MHO) and those with metabolic syndrome (MS) may be useful for understanding the impact of body composition on metabolic health. This cross-sectional study included 193 children aged 6-10 years with obesity (BMI > 95th percentile). Fat and lean mass distributions were measured by dual-energy X-ray absorptiometry to assess body composition. Among the study population, 45.1% were classified as MHO, while 25% presented MS. Compared with children with MHO, those with MS had significantly greater fat mass and lean mass. Body composition was strongly correlated with metabolic dysfunction, including insulin resistance, hypoalphalipoproteinaemia, and hypertriglyceridaemia. These findings reveal a definitive association between body composition indices and metabolic syndrome status in children with obesity. However, not all children with obesity develop metabolic abnormalities, highlighting the importance of detailed body composition analysis in assessing metabolic health risk

Body mass index · Composition (language · Fat mass · Lean body mass · Metabolic disease · Metabolic syndrome · Obesity · Body Composition Measurement Techniques · Diabetes, Cardiovascular Risks, and Lipoproteins · Obesity, Physical Activity, Diet

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