Micronutrient powder supplements combined with nutrition education marginally improve growth amongst children aged 6–23 months in rural Burkina Faso

A cluster randomized controlled trial

Dados Bibliográficos

ID15536622
AutoresHermann Biénou Lanou (0000-0001-6780-2700, Institut de Recherche en Sciences de la Santé, autor correspondente), Saskia Osendarp (0000-0002-3847-5584, Nutrition International), Alemayehu Argaw (0000-0003-3982-5408, Nutrition International), Kirrily de Polnay (Instituut voor Tropische Geneeskunde), Catherine Ouédraogo (Nutrition International), Seni Kouanda (0000-0003-2426-7669, Institut de Recherche en Sciences de la Santé), Patrick Kolsteren (0000-0002-0504-2205, Instituut voor Tropische Geneeskunde)
Ano2019
Volume15
Fascículo4
Páginase12820-e12820
Data de publicação2019-04-03
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoMaternal and Child Nutrition (JOURNAL)
Identificadores do periódicoISSN: 1740-8695 • E-ISSN: 1740-8709
EditoraWiley (PUBLISHER • GB)
DOI10.1111/mcn.12820
PMID30941887
OpenAlexW2927021116
IdiomaEN
Citações recebidas2
Referências citadas47

Micronutrients powder (MNP) can prevent anaemia amongst children 6-23 months old. However, evidence of an effect on growth is limited and concerns about the safety of iron-containing MNP interventions limits their applicability. In a cluster randomized controlled intervention, we evaluated the effectiveness of a nutritional package including counselling and provision of MNP to improve the nutritional status of children aged 6-23 months and the effect of sustained use of MNP on morbidity in a malaria-endemic area. Child feeding practises and nutritional status were assessed through cross-sectional surveys. Biweekly morbidity surveillance and anthropometry measurements were carried out in a nested cohort study. No significant differences in the prevalence of wasting (-0.7% [-6.8, 5.3] points; p = .805), stunting (+4.6% [-2.9, 12.0] points; p = .201), or mean length-for-age z-score and weight-for-length z-score scores were found between study groups. The proportion of children with a minimum dietary diversity score and those with a minimum acceptable diet significantly increased in the intervention group compared with the control by 6.5% points (p = .043) and 5.8% points (p = .037), respectively. There were no significant differences in the risk of diarrhoea (RR: 1.68, 95% CI [0.94, 3.08]), fever (RR: 1.20 [0.82, 1.77]), and malaria (RR: 0.68 [0.37, 1.26]) between study groups. In the nested study, the rate of linear growth was higher in the intervention than in the control group by 0.013 SD/month (p = .027). In a programmatic intervention, MNP and nutrition education marginally improved child feeding practises and growth, without increasing morbidity from malaria or fever

Anthropometry · Cluster randomised controlled trial · Cohort · Dietary diversity · Linear growth · Malaria · Micronutrient · Nutrition Education · Psychological intervention · Randomized controlled trial · Wasting · Child Nutrition and Water Access · Global Maternal and Child Health · Iron Metabolism and Disorders · Medicine · Gerontology · Immunology · Internal Medicine · Pediatrics