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Maternal nutritional status mediates the association between maternal age and birth outcomes

Bibliographic Data

ID15537243
AuthorsAbdulhalik Workicho (0000-0001-8422-1983, Jimma University, corresponding author), Tefera Belachew (0000-0001-5455-9457, Jimma University), Alemayehu Argaw (0000-0003-3982-5408, Jimma University), Alemzewed Roba (Hawassa University), Shibani Ghosh (0000-0001-5893-6774, Tufts University), Meghan Kershaw (0000-0002-3810-9410, Tufts University), Carl Lachat (0000-0002-1389-8855, Ghent University), Patrick Kolsteren (0000-0002-0504-2205, Ghent University)
Year2020
Volume16
Issue4
Pagese13015-e13015
Publication date2020-04-30
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueMaternal and Child Nutrition (JOURNAL)
Journal identifiersISSN: 1740-8695 • E-ISSN: 1740-8709
PublisherWiley (PUBLISHER • GB)
DOI10.1111/mcn.13015
PMID32351001
OpenAlexW3021149302
LanguageEN
Citations received4
References cited29

Young maternal age during pregnancy is linked with adverse birth outcomes. This study examined the role of maternal nutritional status in the association between maternal age and small for gestational age (SGA) delivery and birth length. We used data from a birth cohort study in Ethiopia, involving women who were 15-24 years of age and their newborns. A mediation analysis was fitted in a sample of 1,422 mother infant dyads for whom data on birth length were available, and 777 dyads for whom gestational age and birth weight was measured. We used commands, medeff for the mediation analysis and medsens for sensitivity analysis in STATA 14. Maternal nutritional status, measured by mid-upper arm circumference, mediated 21% of the association between maternal age and birth length and 14% of the association with SGA delivery. The average direct effect (ADE) of maternal age on birth length was (β = 0.45, 95% CI [0.17, 0.99]) and the average causal mediated effect (ACME) was (β = 0.12, 95% CI [0.02, 0.15]). We also found an ADE (β = 0.31, 95% CI [0.09, 0.47]) and an ACME of (β = 0.05, 95% CI [0.003, 0.205]) of maternal age on SGA delivery. The sensitivity analysis suggests an unmeasured confounder with a positive correlation of 0.15 and 0.20 between the mediator and the outcome could explain the observed ACME for birth length and SGA, respectively. We cannot make strong causal assertions as the findings suggest the mediator partly explained the total effect of maternal age on both outcomes

Association (psychology · Birth, Development, and Health · Child Nutrition and Water Access · Demography · Gestational Diabetes Research and Management · Medicine

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Unique citing works4
Citations per year0,8
Citation span2021 - 2025 (5)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 4
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