Hypothetical acceptability of minimally invasive tissue sampling and considerations for practice

A qualitative study in Vietnam

Datos Bibliográficos

ID15541018
AutoresNhung Doan Phuong (0000-0002-1057-3684, Oxford University Clinical Research Unit), Ngan Ta Thi Dieu (0000-0003-4180-6441, Hanoi Medical University), Michelle Nguyen (0000-0001-8694-4456, Oxford University Clinical Research Unit), An Luu Phuoc (Oxford University Clinical Research Unit), Halina Suwalowska (0000-0003-4039-094X, University of Oxford), Duy Manh Nguyen (0000-0002-5497-3954, Grinnell College), Ha Thi Lien Nguyen (Hospital for Tropical Diseases), Huong Thi Thu Vu (0000-0001-8512-2784, Hospital for Tropical Diseases), Thach Ngoc Pham (0000-0003-3472-6355, Hospital for Tropical Diseases), Trung Cap Nguyen (Hospital for Tropical Diseases), Mai Thị Phước Loan, Mary Chambers (0000-0002-7311-9390, University of Oxford), Nghia Ho Dang Trung (0009-0005-6026-9153, Hospital for Tropical Diseases), Jennifer I Van Nuil (0000-0002-5167-5505, University of Oxford, autor de correspondencia), H Rogier Van Doorn (0000-0002-9807-1821, University of Oxford)
Año2024
Volumen19
Número1
Páginas2403097-2403097
Fecha de publicación2024-09-16
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaGlobal Public Health (JOURNAL)
Identificadores de la revistaISSN: 1744-1692 • E-ISSN: 1744-1706
EditorialTaylor & Francis (PUBLISHER • GB)
DOI10.1080/17441692.2024.2403097
PMID39284583
OpenAlexW4402567309
IdiomaEN
Citas recibidas1
Referencias citadas26

The exact aetiology of the cause of death (COD) remains unknown for a high proportion of deaths caused by infectious diseases. Complete diagnostic autopsy (CDA) is considered the gold standard to determine COD, but it is often not used in low and middle-income countries (LMIC), including Vietnam, for a variety of reasons. One alternative is minimally invasive tissue sampling (MITS). This study was part of a larger project to explore the perceptions of MITS in Vietnam to provide recommendations for its potential implementation. We collected in-depth interviews and focus group discussions that explored MITS acceptability from 96 participants, including key informants, healthcare workers, community stakeholders, and people who had family members pass away recently. Participants highlighted the minimally invasive nature as the most considerable strength of MITS that could make it acceptable in Vietnam compared with CDA. However, participants still had concerns including the accuracy of the technique, the potential damage on the body, and the potential conflicts MITS results could have with original clinical diagnoses. Overall, the hypothetical acceptability of MITS was not clear-cut. It is imperative to consider acceptability before implementing new medical procedures into a given context, especially when it revolves around death, dying and the body

Qualitative research · Sampling (signal processing · Social science · Sociology · Computer Science · Ethics in Clinical Research · Healthcare cost, quality, practices · Healthcare Policy and Management · Medicine