Ethical implications of genetic testing of susceptibility to breast cancer
Bibliographic Data
| ID | 15693152 |
|---|---|
| Authors | Nedy Maria Branco Cerqueira Neves (0000-0002-6383-3320, Universidade Salvador, corresponding author), Camila Silva Bôaventura (0000-0002-5268-8084, AC Camargo Hospital), Maria Alice Freitas Costa (0000-0002-8501-4713, AC Camargo Hospital), Almir Galvão Vieira Bitencourt (0000-0003-0192-9885, AC Camargo Hospital) |
| Year | 2022 |
| Volume | 30 |
| Issue | 3 |
| Pages | 636-643 |
| Publication date | 2022-09-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Revista Bioética (JOURNAL) |
| Journal identifiers | ISSN: 1983-8034 • E-ISSN: 1983-8042 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/1983-80422022303557en |
| OpenAlex | W4312700489 |
| Language | EN |
| References cited | 18 |
Breast cancer is a public health problem because it is the malignant neoplasm with the highest incidence in women worldwide. The hereditary form corresponds to about 5% to 10% of all cases and is directly related to the inheritance of genetic mutations. The main ones occur in the BRCA1 and BRCA2 tumor suppressor genes. The identification of these mutations is extremely important because of the high risk of breast cancer development in this population, allowing differentiated screening strategies and the adoption of risk reduction measures. However, reflections on the ethical aspects related to the indiscriminate use of genetic testing are important and necessary. The objective of this study was to evaluate the knowledge and opinion of physicians of an oncology reference center on the indication of genetic tests for susceptibility to breast cancer given the ethical dilemmas to which they are submitted in medical practice
Biology · Breast cancer · Cancer · Disease · Environmental health · Family medicine · Gene · Genetic counseling · Genetic predisposition · Genetic testing · Gynecology · Hereditary Cancer · Incidence (geometry · Inheritance (genetic algorithm · Mutation · Population · BRCA gene mutations in cancer · Ethics in Clinical Research · Genetic factors in colorectal cancer · Medicine · Genetics · Internal Medicine · Oncology
| Highly cited | No |
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