Nasopharyngeal Carriage and Antimicrobial Susceptibility Patterns of Streptococcus pneumoniae among Children under Five in Southwest Ethiopia
Bibliographic Data
| ID | 15712419 |
|---|---|
| Authors | Tiglu Gebre (Jimma University), Mulualem Tadesse (Jimma University, corresponding author), Dossegnaw Aragaw (Jimma University), Dagne Feye (Jimma University), Habtamu B Beyene (Addis Ababa University), Habtamu Beyene (Addis Ababa University), Dinberu Seyoum (Jimma University), Mekidim Mekonnen (Jimma University) |
| Year | 2017 |
| Volume | 4 |
| Issue | 4 |
| Pages | 27-27 |
| Publication date | 2017-04-19 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children4040027 |
| PMID | 28422083 |
| OpenAlex | W2606905070 |
| Language | EN |
| Citations received | 1 |
| References cited | 19 |
Nasopharyngeal carriage of Streptococcus pneumoniae is found to play an important role in the development and transmission of pneumococcal diseases. In this study, we assessed the nasopharyngeal carriage, antimicrobial susceptibility patterns and associated risk factors of S. pneumoniae among children under five. A total of 361 children under five attending the outpatient department of Shanan Gibe Hospital in Jimma, Southwest Ethiopia were enrolled from June to September 2014. Nasopharyngeal specimens were collected using sterile plastic applicator rayon tipped swab and inoculated on tryptone soy agar supplemented with 5% sheep blood and 5 μg/mL gentamycin. Antimicrobial susceptibility testing was performed using the modified disk diffusion method. The overall prevalence of S. pneumoniae carriage was 43.8% (158/361) among children under five. Resistance to tetracycline, cotrimoxazole, penicillin, chloramphenicol and erythromycin was observed in 53.2% (84/158), 43.7% (69/158), 36.1% (57/158), 13.3% (21/158) and 8.9% (14/158) of isolates respectively. Multidrug resistance was seen in 17.7% (28/158) of isolates. In multivariate logistic regression analysis, children living with sibling(s) S. pneumoniae carriage. A high nasopharyngeal carriage of S. pneumoniae was observed among children under five in Southwest Ethiopia. There should be a strategy to prevent S. pneumoniae nasopharyngeal colonization and identify the appropriate antibiotic to the individual child
Antibiotics · Antimicrobial · Biology · Carriage · Pathology · Streptococcus pneumoniae · Bacterial Infections and Vaccines · Medicine · Pneumonia and Respiratory Infections · Streptococcal Infections and Treatments · Microbiology
| Citations per year | 0.25 |
|---|---|
| Citation span | 2022 - 2022 (1) |
| Highly cited | No |