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Effect of Obstructive Sleep Apnea Treatment on Lipids in Obese Children

Bibliographic Data

ID15712455
AuthorsZarlasht Amini (Children's Hospital of Eastern Ontario), Suresh Kotagal (0000-0002-8614-371X, SleepMed), Christine M Lohse (0000-0001-9888-7495, Mayo Clinic), Christine Lohse (Division of Biomedical Statistics and Informatics; Mayo Clinic College of Medicine, Rochester, MN 55905, USA), Robin M Lloyd (SleepMed), Robin Lloyd (Division of Sleep Medicine; Mayo Clinic College of Medicine, Rochester, MN 55905, USA), Swetha Sriram (Mayo Clinic), Seema Kumar (0000-0001-8004-4924, Mayo Clinic, corresponding author)
Year2017
Volume4
Issue6
Pages44-44
Publication date2017-06-01
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children4060044
PMID28587180
OpenAlexW2621285090
LanguageEN
References cited23

Obesity in children is associated with several co-morbidities including dyslipidemia. Obstructive sleep apnea (OSA) is commonly seen in obese children. In adults, diagnosis of OSA independent of obesity is associated with cardiometabolic risk factors including dyslipidemia. There is limited data on the impact of treatment of OSA on lipids in children. The objective of the study was to examine the impact of treatment of OSA on lipids in 24 obese children. Methods: Seventeen children were treated with continuous positive airway pressure (CPAP) and five underwent adenotonsillectomy. Mean apnea hypopnea index prior to treatment was 13.0 + 12.1 and mean body mass index (BMI) was 38.0 + 10.6 kg/m2. Results: Treatment of OSA was associated with improvement in total cholesterol (mean change = -11 mg/dL, p p = 0.021). Conclusion: Obese children should be routinely screened for OSA, as treatment of OSA favorably influences lipids and therefore decreases their cardiovascular risk

Apnea · Cardiology · Obesity · Obstructive sleep apnea · Physical therapy · Sleep (system call · Sleep apnea · Adipose Tissue and Metabolism · Computer Science · Diet and metabolism studies · Medicine · Obesity, Physical Activity, Diet · Internal Medicine · Pediatrics

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