Early-Term Neonates Demonstrate a Higher Likelihood of Requiring Phototherapy Compared to Those Born Full-Term
Bibliographic Data
| ID | 15713157 |
|---|---|
| Authors | Teck-Jin Tan (E-Da Hospital), Wan-Ju Chen (I-Shou University), Wan-Chun Lin (Yuan's General Hospital), Ming‐Chun Yang (0000-0002-5981-5728, E-Da Hospital), Ming-Chun Yang (Department of Pediatrics, E-DA Hospital, I-Shou University, Kaohsiung 82445, Taiwan), Ching‐Chung Tsai (0000-0002-9862-6575), Ching-Chung Tsai (0000-0001-5719-8730, E-Da Hospital), Yung‐Ning Yang (0000-0002-8533-1209, E-Da Hospital), San‐Nan Yang (0000-0003-1276-8546, E-Da Hospital), San-Nan Yang (Department of Pediatrics, E-DA Hospital, I-Shou University, Kaohsiung 82445, Taiwan), Hsien-Kuan Liu (0000-0003-0176-1381, E-Da Hospital, corresponding author) |
| Year | 2023 |
| Volume | 10 |
| Issue | 11 |
| Pages | 1819-1819 |
| Publication date | 2023-11-16 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children10111819 |
| PMID | 38002910 |
| OpenAlex | W4388770693 |
| Language | EN |
| Citations received | 1 |
| References cited | 32 |
Early-term neonates (with a gestational age (GA) of 37 and 0/7 weeks to 38 and 6/7 weeks) face higher morbidities, including respiratory and neurodevelopmental issues, than full-term (39 and 0/7 weeks to 40 and 6/7 weeks) infants. This study explores whether hyperbilirubinemia necessitating phototherapy also differs between these groups. A retrospective study was conducted on neonates born from January 2021-June 2022, excluding those with specific conditions. Evaluated factors included GA, birth weight, bilirubin levels, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and feeding type, with phototherapy given as per AAP guidelines. Of 1085 neonates, 356 met the criteria. When stratifying the neonates based on the need for phototherapy, a higher proportion of early-term neonates required phototherapy compared to full-term ( p < 0.05). After factoring in various risks (GA; birth weight; gender; feeding type; G6PD deficiency; transcutaneous bilirubin levels at 24 h and 24-48 h postpartum; maternal diabetes; and the presence of caput succedaneum or cephalohematoma), early-term neonates were more likely to need phototherapy than full-term babies (OR: 2.15, 95% CI: 1.21 to 3.80). The optimal cut-off for transcutaneous bilirubin levels 24-48 h postpartum that were used to predict phototherapy need was 9.85 mg/dl. In conclusion, early-term neonates are at a greater risk for developing jaundice and requiring phototherapy than full-term neonates. Monitoring bilirubin 24-48 h postpartum enhances early prediction and intervention
Bilirubin · Birth weight · Full Term · Gestational age · Jaundice · Obstetrics · Pregnancy · Medicine · Methemoglobinemia and Tumor Lysis Syndrome · Neonatal Health and Biochemistry · Neonatal Respiratory Health Research · Internal Medicine · Pediatrics · Surgery
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |