Third-Line Antiretroviral Therapy
What Do We Do When the Appropriate Formulations Are Not Available
Bibliographic Data
| ID | 15713504 |
|---|---|
| Authors | Lisa Frigati (0000-0002-4097-3128, Tygerberg Hospital, corresponding author), Helena Rabie (0000-0001-6336-2963, Stellenbosch University) |
| Year | 2022 |
| Volume | 9 |
| Issue | 4 |
| Pages | 473-473 |
| Publication date | 2022-03-30 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children9040473 |
| PMID | 35455517 |
| OpenAlex | W4220719656 |
| Language | EN |
Children on antiretroviral therapy have limited options, particularly if they are failing therapy and live in resource-poor settings. We describe three cases where children accessed third-line antiretroviral therapy off-label, or used them extemporaneously with successful outcomes. We then review the evidence for performing this measure. There is an urgent need for appropriate formulations to treat young children who require a third-line or salvage regimen
Antiretroviral therapy · Antiretroviral treatment · Chemotherapy · First line · Human immunodeficiency virus (HIV · Intensive care medicine · Regimen · Second line · Second-line therapy · Viral load · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Pharmaceutical studies and practices · Internal Medicine · Surgery · Virology
| Highly cited | No |
|---|