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Artificial Womb Technology for Extremely Premature Neonates

Preclinical Neurodevelopmental Outcomes

Bibliographic Data

ID15713576
AuthorsFelix R De Bie (0000-0002-0363-1233, Duke University), Chelsea Zhang (Duke University), Chelsea J Zhang (Duke University), Sharla Rent (0000-0002-8577-478X, Duke University), Jeffrey B Russ (0000-0001-8781-686X, Duke University), Kevin Ig-Izevbekhai (0000-0002-3300-2382, Duke University), Ryan M Antiel (0009-0008-0118-3466, Duke University, corresponding author)
Year2025
Volume13
Issue1
Pages47-47
Publication date2025-12-30
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children13010047
PMID41597055
OpenAlexW7117716686
LanguageEN
References cited111

In this narrative review, we examine current neurological and neurodevelopmental outcomes associated with extreme prematurity, specifically in infants born between 22 and 24 weeks of gestational age. In addition, we explore the scientific and clinical rationale for the development of artificial womb technology and provide an overview of the current state of the art in preclinical models. For each model, we review and analyze the neurological outcomes, including structural, developmental, and functional outcomes, evaluating their limitations in anticipation of imminent clinical translation

Anticipation (artificial intelligence · Gestational age · MEDLINE · Narrative review · Premature birth · Infant Development and Preterm Care · Neonatal and fetal brain pathology · Preterm Birth and Chorioamnionitis

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Highly citedNo

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