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Improving Medication Safety Through Medication Reconciliation in Pediatric Neurology

Clinical Pharmacist Recommendations and Physician Uptake in a 13-Week Study

Bibliographic Data

ID15713620
AuthorsMargherita Zennaro (Azienda Ospedale - Università Padova), Anna Trotter (University of Padua), Daniele Mengato (0000-0003-1374-1505, Azienda Ospedale - Università Padova, corresponding author), Laura Camuffo (0009-0001-8710-486X, Azienda Ospedale - Università Padova), Claudio Ancona (University of Padua), Irene Toldo (0000-0002-0006-3381, University of Padua), Maria Cecilia Giron (0000-0002-0825-7965, University of Padua), Maria Federica Pelizza (University of Padua), Margherita Nosadini (0000-0002-6395-7614, University of Padua), Giorgio Perilongo (0000-0002-3712-0386, University of Padua), Stefano Sartori (0000-0002-0012-6848, University of Padua), Francesca Venturini (0000-0003-2562-9932, Azienda Ospedale - Università Padova)
Year2025
Volume12
Issue5
Pages625-625
Publication date2025-05-12
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children12050625
PMID40426804
OpenAlexW4410286927
LanguageEN
Citations received2
References cited11

Background/Objectives: Clinical pharmacy plays a crucial role in optimizing medication use, particularly in pediatric settings where drug therapy can be complex and understudied. This study aims to assess the impact of clinical pharmacists in the Pediatric Neurology and Neurophysiology Unit of the Padova University Hospital, focusing on physician acceptance of pharmacist suggestions and the types of advice most frequently followed. Methods: A retrospective observational study was conducted over 13 weeks to describe the implementation phase of clinical pharmacists' involvement in medication reconciliation in this setting. The study consisted of three steps. The study utilized a cluster model to categorize pharmacist suggestions and to evaluate physician acceptance rates. Results: The study included 57 hospitalized pediatric patients (53% male) with a median age of 3 years (IQR: 1-10.25). A total of 138 recommendations were shared, with an overall acceptance rate of 42%. Medication errors accounted for the largest cluster of suggestions (45%), though only 32% were accepted. Among the most frequently shared categories of suggestions, pharmaceutical form optimization (A) and drug supply (E) exhibited higher acceptance rates by clinicians (64% and 42%, respectively). The acceptance rate increased over time, peaking at 100% during weeks 7 and 11, correlating positively with enhanced collaboration between pharmacists and clinicians (R 2 = 0.59). Conclusions: This study highlights the importance of clinical pharmacists in pediatric care, particularly in improving medication management through targeted interventions. The findings suggest that integrating clinical pharmacists into multidisciplinary teams can enhance patient care quality by fostering collaboration and trust among healthcare professionals

Clinical pharmacy · Family medicine · Health care · Medical emergency · Medication Reconciliation · Patient safety · Pediatric Neurology · Pharmacist · Psychiatry · Medicine · Patient Safety and Medication Errors · Pharmaceutical Practices and Patient Outcomes · Pharmaceutical studies and practices · Neurology · Pediatrics · Pharmacy

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Citations per year2
Citation span2026 - 2026 (1)
Highly citedNo

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Open DOIOpen Access
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