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Neonatal Outcomes of Term Infants Born with Meconium-Stained Amniotic Fluid

Bibliographic Data

ID15714526
AuthorsCarlo Dani (0000-0002-1639-621X, Azienda Ospedaliero-Universitaria Careggi, corresponding author), Martina Ciarcià (0000-0001-6957-4609, Azienda Ospedaliero-Universitaria Careggi), Vittoria Barone (University of Florence), Mariarosaria Di Tommaso (0000-0001-8248-929X, University of Florence), Federico Mecacci (0000-0002-2467-1875, University of Florence), Lucia Pasquini (0000-0002-6733-7658, Azienda Ospedaliero-Universitaria Careggi), Simone Pratesi (0000-0002-8943-7246, Azienda Ospedaliero-Universitaria Careggi)
Year2023
Volume10
Issue5
Pages780-780
Publication date2023-04-26
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children10050780
PMID37238328
OpenAlexW4367052086
LanguageEN
Citations received1
References cited25

Background Meconium-stained amniotic fluid (MSAF) is considered an alarming sign of possible fetal compromise and it has recently been reported that neonatal outcome correlates with the degree of meconium thickness. Methods We retrospectively studied 400 term infants allocated in clear amniotic fluid and grade 1, 2, and 3 MSAF groups on the basis of color and thickness of AF. Multivariable logistic regression analysis was performed to evaluate the potential independent effect of delivery with MSAF of different severity on the risk of a composite adverse neonatal outcome. Results We found that delivery with grade 2 (OR 16.82, 95% Cl 2.12-33.52; p = 0.008) and 3 (OR 33.79, 95% Cl 4.24-69.33; p Conclusions There is a positive correlation between the severity of amniotic fluid meconium staining and thickness and the outcomes of term infants. Therefore, the evaluation and grading of MSAF during labor is useful in order to plan for the presence of a neonatologist at delivery for immediate and proper neonatal care

Amniotic fluid · Anesthesia · Fetal distress · Fetus · Gestational age · Meconium · Meconium aspiration syndrome · Neonatal intensive care unit · Obstetrics · Pregnancy · Respiratory distress · Medicine · Neonatal and fetal brain pathology · Neonatal Respiratory Health Research · Neuroscience of respiration and sleep · Pediatrics

  • Association of Meconium-Stained Amniotic Fluid and Histological Chorioamnionitis with Fetal Inflammatory Response in Preterm Deliveries

    Open Access•Dóra Balogh, Dóra Csenge Balogh et al.•Children•2025

  • Approach to the Connection between Meconium Consistency and Adverse Neonatal Outcomes

    Open Access•Hueng‐Chuen Fan, Fung-Wei Chang et al.•Children•2021

Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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Open DOIOpen Access
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