Diet and Lipid-Lowering Nutraceuticals in Pediatric Patients with Familial Hypercholesterolemia
Bibliographic Data
| ID | 15714670 |
|---|---|
| Authors | Maria Elena Capra (0000-0003-0848-5228, University of Parma), Giacomo Biasucci (0000-0002-7441-9248, Guglielmo da Saliceto Hospital), Giuseppe Banderali (0000-0001-6650-981X, Ospedale San Paolo), Andrea Vania (0000-0001-6158-2495, Independent Researcher, Member of SINUPE (Italian Society of Pediatric Nutrition) Directory Board, 00162 Rome, Italy, corresponding author), Cristina Pederiva (0000-0002-2213-9383, Ospedale San Paolo) |
| Year | 2024 |
| Volume | 11 |
| Issue | 2 |
| Pages | 250-250 |
| Publication date | 2024-02-15 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children11020250 |
| PMID | 38397362 |
| OpenAlex | W4391844943 |
| Language | EN |
| References cited | 77 |
Familial hypercholesterolemia is a genetically determined disease characterized by elevated plasma total and LDL cholesterol levels from the very first years of life, leading to early atherosclerosis. Nutritional intervention is the first-line treatment, complemented with nutraceuticals and drug therapy when necessary. Nutraceuticals with a lipid-lowering effect have been extensively studied in the past few decades, and have been recently included in international guidelines as a complement to nutritional and pharmacological treatment in subjects with dyslipidemia. In this review, we explore current nutritional interventions for dyslipidemia in childhood, with a specific focus on the main nutraceuticals studied for treating severe dyslipidemia in pediatric patients. Additionally, we briefly describe their primary mechanisms of action and highlight the advantages and risks associated with the use of lipid-lowering nutraceuticals in childhood
Cholesterol · Disease · Dyslipidemia · Familial hypercholesterolemia · Nutraceutical · Pathology · Cancer, Lipids, and Metabolism · Cholesterol and Lipid Metabolism · Lipoproteins and Cardiovascular Health · Medicine · Internal Medicine
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ESC Guidelines on cardiovascular disease prevention in clinical practice
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Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins
| Highly cited | No |
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