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Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center

Bibliographic Data

ID15714922
AuthorsClaudia Felicia Pop (0000-0001-5030-3753, Iuliu Hațieganu University of Medicine and Pharmacy), Alina Petronela Bouari-Coblișan (0000-0003-4635-240X, Iuliu Hațieganu University of Medicine and Pharmacy, corresponding author), Petronela Coblisan (Department of Mother and Child, Nursing Discipline, Faculty of Medicine, University of Medicine and Pharmacy Ïuliu Hatíeganu, 400124 Cluj-Napoca, Romania), Ligia Capalna (Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor), Paraschiva Cherecheș-Panța (0000-0001-7427-0191, Iuliu Hațieganu University of Medicine and Pharmacy), Anca Dana Buzoianu (0000-0002-3511-2788, Iuliu Hațieganu University of Medicine and Pharmacy), Ioana Corina Bocșan (0000-0002-3279-5384, Iuliu Hațieganu University of Medicine and Pharmacy)
Year2023
Volume10
Issue1
Pages104-104
Publication date2023-01-04
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children10010104
PMID36670654
OpenAlexW4313585659
LanguageEN
References cited34

Vaccines represent an important preventive strategy in paediatric populations, but the rate of vaccination has been constantly declining in the last decade. Concerns about vaccines' safety represent one of the main causes of vaccine hesitancy among parents. The aim of this study was the analysis of the immediate adverse reactions induced by vaccines included in the national program of immunization for the first year of life. Method: Eighty-one children born between 1st of January 2018 and 31st of March 2019 were included. The vaccination refusal rate, and incidence and severity of adverse effects induced by three mandatory vaccines (Hexavalent, Prevenar 13 and MMR) were analyzed. The level of parents' education and the sources of information that were consulted in order to understand the adverse effects were also analyzed. Results and conclusions: The rate of adverse events was lower than 30% of the total number of doses, and most of them were mild. The incidence and severity of vaccine-induced adverse effects were correlated with prematurity. The vaccine hesitancy rate was lower than the national one, possibly due to a high level of education and good information provided by doctors that might have led to parents' concerns regarding vaccination being answered

Adverse effect · Family medicine · Immunization · Immunization program · Incidence (geometry · Vaccination · Ethics and Legal Issues in Pediatric Healthcare · Influenza Virus Research Studies · Medicine · Vaccine Coverage and Hesitancy · Immunology · Internal Medicine · Pediatrics

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    Open Access•Heidi J Larson, Antero De Figueiredo et al.•EBioMedicine•2016

  • Vaccine hesitancy

    Open Access•Noni E Macdonald•Vaccine•2015

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