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Vitamin D Level and Immune Modulation in Children with Recurrent Wheezing

Bibliographic Data

ID15714935
AuthorsGavriela Feketea (0000-0001-9026-2597, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca), Εmilia Vassilopoulou (0000-0002-2665-5908, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, corresponding author), Oana Andreescu (Transylvania University of Brașov), Camelia Elena Berghea (0000-0001-9522-8363, Carol Davila University of Medicine and Pharmacy), Raluca Maria Pop (0000-0003-1899-5977, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca), Octavia Sabin (0000-0003-4457-8456, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca), Mihnea Zdrenghea (0000-0002-9461-987X, Iuliu Hațieganu University of Medicine and Pharmacy), Ioana Corina Bocșan (0000-0002-3279-5384, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca)
Year2024
Volume11
Issue2
Pages219-219
Publication date2024-02-08
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11020219
PMID38397331
OpenAlexW4391642853
LanguageEN
References cited41

The vit D level was lower in patients with recurrent wheezing compared with those with a single episode and with the control group, and this increased with time. IL-10 was significantly higher in children with wheezing than in the control group, with the highest values in those with an acute episode of wheezing. IL-31 was higher in children with recurrent wheezing than in those with a first episode only at the initial point, while at the final time point it was lower. Low levels of vit D appear to be detected more frequently in recurrent wheezing than in simple wheezing. Immune modulation, as measured by Th2 status reflected by IL-10 and IL-31 levels, appears to depend on the wheezing phenotype and on the general health status

Asthma · Immune system · Pre school · Vitamin D and neurology · Asthma and respiratory diseases · Medicine · Neonatal Respiratory Health Research · Vitamin D Research Studies · Immunology · Internal Medicine · Pediatrics

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Highly citedNo

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