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Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents

Results of a Survey Study amongst Practitioners

Bibliographic Data

ID15716232
AuthorsThomas G de Leeuw (0000-0001-9516-3088, Erasmus MC - Sophia Children’s Hospital, corresponding author), Tjitske der Zanden (Erasmus MC - Sophia Children’s Hospital), S Ravera (0000-0002-3976-0985, PHARM (Italy)), Mariagrazia Felisi (0000-0002-7315-0857, PHARM (Italy)), Donato Bonifazi (0000-0003-2636-9159, Consorzio per Valutazioni Biologiche e Farmacologiche), Dick Tibboel (0000-0003-4331-5398, Erasmus MC - Sophia Children’s Hospital), Adriana Ceci (0000-0002-8778-3612, Gianni Benzi Pharmacological Research Foundation), Florentia Kaguelidou (0000-0002-7842-5602, Inserm), Saskia N de Wildt (0000-0002-0502-0647, Radboud University Nijmegen)
Year2020
Volume7
Issue11
Pages208-208
Publication date2020-11-02
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children7110208
PMID33147808
OpenAlexW3097166842
LanguageEN
Citations received1
References cited36

Validated diagnostic tools to diagnose chronic neuropathic and mixed pain in children are missing. Therapeutic options are often derived from therapeutics for adults. To investigate the international practice amongst practitioners for the diagnosis and treatment of chronic, neuropathic pain in children and adolescents, we performed a survey study among members of learned societies or groups whose members are known to treat pediatric pain. The survey included questions concerning practitioners and practice characteristics, assessment and diagnosis, treatment and medication. We analyzed 117 returned questionnaires, of which 41 (35%) were fully completed and 76 (65%) were partially completed. Most respondents based the diagnosis of neuropathic pain on physical examination (68 (58.1%)), patient history (67 (57.3%)), and underlying disease (59 (50.4%)) combined. Gabapentin, amitriptyline, and pregabalin were the first-choice treatments for moderate neuropathic pain. Tramadol, ibuprofen, amitriptyline, and paracetamol were the first-choice treatments for moderate mixed pain. Consensus on the diagnostic process of neuropathic pain in children and adolescents is lacking. Drug treatment varies widely for moderate, severe neuropathic, and mixed pain. Hence, diagnostic tools and therapy need to be harmonized and validated for use in children

Alternative medicine · Amitriptyline · Analgesic · Anesthesia · Carbamazepine · Chronic pain · Epilepsy · Gabapentin · Neuropathic pain · Physical therapy · Pregabalin · Psychiatry · Tramadol · Medicine · Musculoskeletal pain and rehabilitation · Pain Mechanisms and Treatments · Pediatric Pain Management Techniques

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Citations per year0.2
Citation span2021 - 2021 (1)
Highly citedNo

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