A Case of Covid-19-Related Thrombocytopenia and Leukopenia in an Adolescent with Mild Symptoms

Bibliographic Data

ID15716690
AuthorsLydia Kossiva (0000-0002-0476-6586, Panagiotis & Aglaia Kyriakou Children's Hospital), Athanasios Thirios (National and Kapodistrian University of Athens), Eleni Panagouli (0000-0002-8764-1059, Panagiotis & Aglaia Kyriakou Children's Hospital), Alexandros Panos (Panagiotis & Aglaia Kyriakou Children's Hospital), Stavroula Lampidi (National and Kapodistrian University of Athens), Flora Bacopoulou (0000-0003-1001-0926, National and Kapodistrian University of Athens), Μαρία Τσολιά (0000-0003-2485-4409, National and Kapodistrian University of Athens), Maria Tsolia (National and Kapodistrian University of Athens), Άρτεμις Τσίτσικα (0000-0002-8436-640X, Panagiotis & Aglaia Kyriakou Children's Hospital, corresponding author), Artemis Tsitsika (National and Kapodistrian University of Athens)
Year2021
Volume8
Issue6
Pages509-509
Publication date2021-06-16
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children8060509
PMID34208610
OpenAlexW3170989195
LanguageEN
References cited35

Since the beginning of the COVID-19 pandemic, there have been numerous reports and reviews on the complications caused by the disease, analyzing the acute and chronic consequences. The main symptoms of SARS-CoV-2 are dry cough, fever, and fatigue. COVID-19 appears to affect all systems, including renal, cardiovascular, circulatory, and respiratory systems, causing chronic obstructive pulmonary disease. We report on a 14-year-old male adolescent, who presented with thrombocytopenia (platelet count 92 × 10 9 /L) and leukopenia (white blood count 4.2 × 10 3 /μL) that was observed two months ago. Ten days before the first blood test, a viral infection with nasal congestion and runny nose was reported, without other accompanying symptoms. Viral antibodies screening revealed positivity for all the three specific COVID-19 antibodies. Further haematological evaluation with bone marrow aspiration revealed non-specific dysplastic features of the red cell and megakaryocyte progenitors. Although haematological alterations due to COVID-19 infection are available from adult patients' reports, the effect of COVID-19 infection in the pediatric population is underestimated and this is the first case with such haematological involvement. Noteworthy, in the current case, the impact of the COVID-19 infection was not related to the severity of the disease, as the symptoms were mild. In similar cases, bone marrow aspiration would not be performed as a part of routine work-up. Thus, it is important when evaluating pediatric patients with COVID-19 infection to search and report those alterations in order to better understand the impact and the spectrum of clinical manifestations of the specific viral infection in children and adolescents

Bone marrow · Coronavirus disease 2019 (COVID-19 · Disease · Infectious disease (medical specialty · Leukopenia · Nasal congestion · Nose · Population · White blood cell · COVID-19 Clinical Research Studies · Dermatological and COVID-19 studies · Kawasaki Disease and Coronary Complications · Medicine · Immunology · Internal Medicine · Pediatrics · Surgery

Tools

Open DOIOpen Access