Using the MDASI-Adolescent for Early Symptom Identification and Mitigation of Symptom Impact on Daily Living in Adolescent and Young Adult Stem Cell Transplant Patients

Bibliographic Data

ID15716835
AuthorsIrtiza Sheikh (The University of Texas MD Anderson Cancer Center, corresponding author), Jeffrey D Miller (0000-0002-7916-6366, The University of Texas MD Anderson Cancer Center), Basirat Shoberu (The University of Texas MD Anderson Cancer Center), Clark R Andersen (0000-0003-1846-9117, The University of Texas MD Anderson Cancer Center), Jian Wang (0000-0001-6128-1254, The University of Texas MD Anderson Cancer Center), Loretta A Williams (0000-0003-2788-657X, The University of Texas MD Anderson Cancer Center), Kris M Mahadeo (0000-0003-2649-9674, The University of Texas MD Anderson Cancer Center), Rhonda Robert (0000-0002-8123-9085, The University of Texas MD Anderson Cancer Center, corresponding author)
Year2021
Volume9
Issue1
Pages19-19
Publication date2021-12-29
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children9010019
PMID35053644
OpenAlexW4200491878
LanguageEN
Citations received1
References cited4

Hematopoietic stem cell transplantation (HSCT) requires an intensive pre- and post-procedure course that leads to symptoms including fatigue, nausea/vomiting, and pain, all of which interfere significantly with activities of daily living. These symptoms place a substantial burden on patients during the time period surrounding transplant as well as during long-term recovery. The MD Anderson Symptom Inventory (MDASI) is a symptom-reporting survey that has been successfully used in adult patients with cancer and may have utility in the adolescent and young adult (AYA) population. At the Children's Cancer Hospital at MD Anderson Cancer Center, we adopted a modified version of the MDASI, the MDASI-adolescent (MDASI-Adol), as a standard of care for clinical practice in assessing the symptom burden of patients in the peri-transplant period. We then conducted a retrospective chart review to describe the clinical utility of implementing this symptom-screening tool in AYA patients admitted to our pediatric stem cell transplant service. Here, we report our findings on the symptom burden experienced by pediatric and AYA patients undergoing stem cell transplantation as reported on the MDASI-Adol. Our study confirmed that the MDASI-Adol was able to identify a high symptom burden related to HSCT in the AYA population and that it can be used to guide symptom-specific interventions prior to transplant and during recovery. Implementing a standard symptom-screening survey proved informative to our clinical practice and could mitigate treatment complications and alleviate symptom burden

Nausea · Physical therapy · Population · Stem cell · Young adult · Cancer survivorship and care · Childhood Cancer Survivors' Quality of Life · Hematopoietic Stem Cell Transplantation · Medicine · Palliative Care and End-of-Life Issues · Internal Medicine · Pediatrics · Transplantation

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