Cardiac Manifestations in Children with Sars-COV-2 Infection
1-Year Pediatric Multicenter Experience
Bibliographic Data
| ID | 15716882 |
|---|---|
| Authors | Nicoletta Cantarutti (0000-0001-9888-2395, Bambino Gesù Children's Hospital, corresponding author), Virginia Battista (Bambino Gesù Children's Hospital), Rachele Adorisio (0000-0002-9577-2155, Bambino Gesù Children's Hospital), Marianna Cicenia (0000-0001-7577-6848, Bambino Gesù Children's Hospital), Claudia Campanello (0000-0002-5022-2037, University of Genoa), Elisa Listo (0000-0001-8648-5448, University of Genoa), Andrea Campana (0000-0001-8097-0215, Istituti di Ricovero e Cura a Carattere Scientifico), Gianluca Trocchio (0000-0002-5069-7067, Istituto Giannina Gaslini), Fabrizio Drago (0000-0002-8591-7103, Bambino Gesù Children's Hospital) |
| Year | 2021 |
| Volume | 8 |
| Issue | 8 |
| Pages | 717-717 |
| Publication date | 2021-08-23 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children8080717 |
| PMID | 34438608 |
| OpenAlex | W3194124426 |
| Language | EN |
| Citations received | 3 |
| References cited | 32 |
Since the spread of COVID-19, pediatric patients were initially considered less affected by SARS-COV-2, but current literature reported subsets of children with multisystem inflammatory syndrome (MIS-C). This study aims to describe the cardiac manifestation of SARS-COV-2 infection in a large cohort of children admitted to two Italian pediatric referral centers. Between March 2020 and March 2021, we performed a cardiac evaluation in 294 children (mean age 9 ± 5.9 years, male 60%) with active or previous SARS-COV-2 infection. Twenty-six showed ECG abnormalities: 63 repolarization anomalies, 13 Long QTc, five premature ventricular beats, two non-sustained ventricular tachycardia, and one atrial fibrillation. In total, 146 patients underwent cardiac biomarkers: NT-proBNP was elevated in 57, troponin in 34. An echocardiogram was performed in 98, showing 54 cardiac anomalies: 27 left-ventricular dysfunction, 42 pericarditis, 16 coronaritis. MIS-C was documented in 46 patients (mean age 9 ± 4.8 years, male 61%) with cardiac manifestations in 97.8%: 27 ventricular dysfunctions, 32 pericarditis, 15 coronaritis, 3 arrhythmias. All patients recovered, and during follow-up, no cardiac anomalies were recorded. Our experience showed that cardiac involvement is not rare in children with SARS-COV-2, and occurred in almost all patients with MIS-C. However, patients' recovery is satisfactory and no additional events were reported during FU
Cardiology · Cohort · Myocarditis · Pericarditis · Ventricular tachycardia · Coronary Artery Anomalies · Kawasaki Disease and Coronary Complications · Medicine · Pericarditis and Cardiac Tamponade · Internal Medicine · Pediatrics
Covid-19-Associated Paediatric Inflammatory Multisystem Syndrome (Pims-TS) in Intensive Care
Doenças Infecciosas Na Infância E Seus Agentes Patogênicos Que Causam Insuficiência Cardíaca
Cardiovascular Manifestations in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Covid-19 According to Age
| Citations per year | 0.75 |
|---|---|
| Citation span | 2022 - 2024 (3) |
| Highly cited | No |