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Involvement of Maternal and Socioeconomic Risk Factors in the Incidence of Fetal Growth Restriction in a Large Maternity Hospital in Romania

Bibliographic Data

ID15716978
AuthorsMariana-Lăcrămioara Bucur-Grosu (Clinical Emergency Hospital Bucharest), Andreea Avasiloaiei (0000-0002-5187-9938, Clinical Emergency Hospital Bucharest, corresponding author), Iolanda Valentina Popa (0000-0002-0597-8839, Grigore T. Popa University of Medicine and Pharmacy), Luminița Păduraru (0000-0002-3850-797X, Clinical Emergency Hospital Bucharest), Daniela Cristina Dimitriu (0000-0002-8816-4426, Clinical Emergency Hospital Bucharest), Demetra Socolov (0000-0002-0979-0200, Clinical Emergency Hospital Bucharest)
Year2025
Volume12
Issue2
Pages152-152
Publication date2025-01-28
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children12020152
PMID40003254
OpenAlexW4406911105
LanguageEN
Citations received1
References cited22

Background: Fetal growth restriction (FGR) refers to a condition in which a fetus does not reach its genetically predetermined growth potential due to various pathological factors of maternal or fetal origin, with potential long-life consequences, such as elevated blood pressure, type 2 diabetes mellitus, obesity, dyslipidemia, atherosclerosis. Aim: The purpose of our research is to delve into the intricate relationship between economic and social factors and the occurrence of FGR. Methods: We analyzed risk factors previously associated with FGR and aimed to compare them between two cohorts of infants with FGR: a historical cohort of infants born from 2010 to 2012 and a contemporary cohort of infants born from 2020 to 2022. Results: The global incidence of FGR in our study was 5.13%, with non-significant differences between the two time periods: 5.03% in the historical cohort and 5.25% in the contemporary cohort. More mothers of FGR infants receive formal education and are employed in the contemporary group and thus have a more stable income. There was a major decrease in the number of preterm infants with FGR, from 23.9% in the historical cohort to 5.9% in the contemporary cohort ( p p p p Conclusions: Certain socioeconomic factors show definite improvements over the ten-year timespan, which results in an increase in prenatal care and a decrease in the rate of prematurity. However, the incidence of FGR remains constant over the considered period, meaning that other factors, apart from socioeconomic factors, play a substantial role. Recognizing these risk factors is crucial for developing effective public health strategies aimed at reducing the incidence of FGR and improving maternal and child outcomes

Biology · Cohort · Cohort study · Diabetes mellitus · Dyslipidemia · Environmental health · Fetal growth · Fetus · Incidence (geometry · Obstetrics · Population · Pregnancy · Socioeconomic status · Birth, Development, and Health · Demography · Gestational Diabetes Research and Management · Medicine · Pregnancy and preeclampsia studies · Endocrinology · Internal Medicine · Pediatrics

  • Prematurity and Multidimensional Risk Patterns in Adolescent and Adult Pregnancies

    Open Access•Florin Țovîrnac, Alina Mihaela Călin et al.•Children•2025

  • The origins of the developmental origins theory

    Open Access•David J P Barker•Journal of Internal Medicine•2007

  • Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease.

    Open Access•D J P Barker, D J Barker et al.•BMJ•1989

Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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