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Acute Glomerulonephritis Following Systemic Scabies in Two Brothers

Bibliographic Data

ID15716994
AuthorsFlavia Chisavu (0000-0001-9456-4517, Victor Babeș University of Medicine and Pharmacy Timișoara), Mihai Gafencu (0000-0002-9029-5919, Victor Babeș University of Medicine and Pharmacy Timișoara, corresponding author), Ruxandra Maria Steflea (0000-0002-8033-4785, Victor Babeș University of Medicine and Pharmacy Timișoara), Adrian Văduva (0000-0001-9261-5309, Victor Babeș University of Medicine and Pharmacy Timișoara), Floriana Izvernariu (Intensive Care Unit, “Louis Turcanu” Children’s Clinical and Emergency Hospital, Iosif Nemoianu 2, 300011 Timisoara, Romania), Ramona Stroescu (0000-0002-4403-0581, Victor Babeș University of Medicine and Pharmacy Timișoara)
Year2024
Volume11
Issue8
Pages981-981
Publication date2024-08-14
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11080981
PMID39201916
OpenAlexW4401579897
LanguageEN
Citations received1
References cited29

Scabies is a parasitic infestation of the skin with high prevalence in crowded spaces. In some instances, scabies becomes the underlying factor for complicated skin-borne opportunistic pathogens infections in both children and adults. Geographic area and socio-economic factors are determinants of the endemic pattern of this disease. Currently, the treatment of scabies has been under special attention. A combination of oral therapy with Ivermectin and sulfur-based ointments are the gold standard. However, caution is required in patients with kidney impairment. The renal involvement in children with scabies is mainly caused by acute glomerulonephritis. The severity of the nephritic syndrome can lead to other complications. Also, Ivermectin possesses a nephrotoxic effect. Severe hypertension can lead to neurological complications. The aim of our case report is to present two unusual complications in brothers with scabies. We report the cases of two brothers with scabies who presented with severe skin infection that developed acute post infectious glomerulonephritis (APIGN). In addition, one of the brothers presented with posterior reversible encephalopathy syndrome (PRES). The other one developed acute tubule-interstitial acute kidney injury following Ivermectin administration. The evolution of skin lesions was favorable, and kidney function returned to normal in both brothers

Acute kidney injury · Biology · Glomerulonephritis · Ivermectin · Kidney · Kidney disease · Nephritic syndrome · Renal function · Scabies · Skin infection · Staphylococcus aureus · Veterinary medicine · Body Image and Dysmorphia Studies · Dermatological diseases and infestations · Medicine · Syphilis Diagnosis and Treatment · Dermatology · Internal Medicine

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Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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