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Utility of the TG/HDL-C Ratio in Estimating Pediatric Cardiometabolic Risk in a Community Hospital

Bibliographic Data

ID15717299
AuthorsAdeola Awujoola (0000-0003-1729-9443, Duke University Hospital, corresponding author), Ana Patricia Torga (0009-0000-5737-0289, Children's National), J Valencia (0000-0003-2997-2121, Montefiore Health System), Hermella Alemneh (Washington State University), Olaseni Prince (0000-0001-6714-6782, Montefiore Health System), S Kant (0000-0001-7905-0454, Montefiore Health System)
Year2024
Volume11
Issue11
Pages1277-1277
Publication date2024-10-23
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11111277
PMID39594852
OpenAlexW4403688315
LanguageEN
Citations received1
References cited2

Background : The evaluation of metabolic syndrome (MetS) is critical among children and adolescents as it can predict cardiovascular disease in adulthood. The TG/HDL-C ratio has the best predictive accuracy among the different lipid ratios. This study aims to evaluate the prevalence and factors associated with a high TG/HDL-C ratio and the predictive accuracy for pediatric MetS. Methods : This is a cross-sectional study of adolescents aged 9-21 to determine the prevalence of and associations between an elevated TG/HDL-C ratio and MetS. A ROC curve analysis was performed to determine the predictive accuracy of TG/HDL-C with MetS. Results : Of the 604 subjects, 29.8% had elevated TG/HDL-C, MetS was identified in 28.2%, and 54.5% were obese. Among patients with MetS, those with obesity were more likely to have an elevated TG/HDL-C ratio compared to those with a normal BMI (64% vs. 14%, p p Conclusions : The TG/HDL-C ratio was able to distinguish between children and adolescents with MetS. Hence, the TG/HDL-C ratio may be used in the rapid risk assessment of pediatric MetS, especially in those with obesity

Environmental health · Cardiovascular Function and Risk Factors · Diabetes Management and Research · Hyperglycemia and glycemic control in critically ill and hospitalized patients · Medicine · Internal Medicine

  • The Predictive Role of the Triglyceride/High-Density Lipoprotein Ratio and the Triglyceride–Glucose Index, Along with Anthropometric Measurements, in Diagnosing Non-Alcoholic Fatty Liver Disease in Obese Kids and Juveniles, and the Evaluation of Novel Cardiovascular Risk Markers in Pediatric NAFLD

    Open Access•Emrah Çığrı, Funda Çatan et al.•Children•2025

  • Association between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children and Young Adults

    Gerald S Berenson, Sathanur R Srinivasan et al.•New England Journal of Medicine•1998

  • Diagnosis and Management of the Metabolic Syndrome

    Scott M Grundy, James I Cleeman et al.•Circulation•2005

Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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Open DOIOpen Access
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