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Enteroviral Rhombencephalitis with Abducens Nerve Palsy and Cardio-Pulmonary Failure in a 2-Year-Old Boy

Bibliographic Data

ID15717845
AuthorsChien‐yu Lin (0000-0002-5263-8730, Mackay Memorial Hospital), Chien-Yu Lin (0000-0003-0118-3112, Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan), Shih-Yu Huang (Mackay Memorial Hospital), Chuen‐Bin Jiang (0000-0003-2763-3476, Mackay Medical College), Chun-Chih Peng (0000-0003-3667-5512, Mackay Medical College), Hsin Chi (0000-0002-2385-344X, Mackay Medical College), Nan-Chang Chiu (0000-0002-3966-5021, Mackay Medical College, corresponding author)
Year2022
Volume9
Issue5
Pages643-643
Publication date2022-04-29
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children9050643
PMID35626820
OpenAlexW4229017808
LanguageEN
References cited17

Enterovirus infection is endemic in many areas, especially in Southeast Asia. Enterovirus infection with severe complications (EVSC) is life-threatening, and timely diagnosis and management are crucial for successful management. Here, we report on a 2-year-old boy with hand, foot, and mouth disease. Myoclonic jerks developed and left abducens nerve palsy followed. Brain magnetic resonance imaging (MRI) showed rhombencephalitis. Pulmonary edema and cardiopulmonary failure developed, and intravenous immunoglobulin and extracorporeal membrane oxygenation were administered. He had a tracheostomy with home ventilator use after 64 days of hospitalization. At a 5-year follow-up, his neurodevelopment was normal with complete recovery from the abducens nerve palsy. The progress of EVSC may be rapid and fulminant, and timely diagnosis is critical for patient prognosis and outcomes. The presence of abducens nerve palsy is an indicator of enteroviral rhombencephalitis, and immediate and appropriate management is suggested

Abducens nerve · Anesthesia · Extracorporeal membrane oxygenation · Fulminant · Palsy · Paralysis · Pathology · Medicine · RNA regulation and disease · Viral Infections and Immunology Research · Whipple's Disease and Interleukins · Pediatrics · Surgery

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Highly citedNo

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