Predictive Factors of Persistent Growth Hormone Deficiency and Impact on Final Height

Bibliographic Data

ID15718221
AuthorsFlavia Urbano (0000-0002-9985-7084, Ospedale Pediatrico Giovanni XXIII), Mariangela Chiarito (0000-0003-1996-6270, Ospedale Pediatrico Giovanni XXIII), Luigi Antonio Moscogiuri (Ospedale Pediatrico Giovanni XXIII), Crescenza Lattanzio (Ospedale Pediatrico Giovanni XXIII), Raffaele Vitale (0000-0002-7497-1673, Ospedale Pediatrico Giovanni XXIII), Rossella Vitale (Pediatric Hospital “Giovanni XXIII”, 70126 Bari, Italy), Orazio Valerio Giannico (0000-0001-5375-8841, Unit of Statistics and Epidemiology, Local Health Authority of Taranto, 74121 Taranto, Italy), Grazia Annesi (0000-0001-9951-8798, Ospedale Pediatrico Giovanni XXIII), Gabriele Annesi (Pediatric Hospital “Giovanni XXIII”, 70126 Bari, Italy), Clara Zecchino (Ospedale Pediatrico Giovanni XXIII), Maria Felicia Faienza (0000-0002-1899-8337, University of Bari Aldo Moro, corresponding author)
Year2025
Volume12
Issue3
Pages324-324
Publication date2025-03-03
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children12030324
PMID40150606
OpenAlexW4408113649
LanguageEN
References cited25

Our study confirmed that the most important predictor of persistent GHD is the growth rate in the first year of therapy. Furthermore, growth rate in the first year, female gender, and lower BA at diagnosis are predictors of rhGH efficacy both in terms of height gain and target height achievement

Anthropometry · Bone age · Cohort · Growth hormone · Growth hormone deficiency · Hormone · Multivariate analysis · Univariate analysis · Genetic Syndromes and Imprinting · Growth Hormone and Insulin-like Growth Factors · Medicine · Metabolism and Genetic Disorders · Endocrinology · Internal Medicine · Pediatrics

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