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Follistatin Is Associated with Bone Mineral Density in Lean Adolescent Girls with Increased Physical Activity

Bibliographic Data

ID15718421
AuthorsJaak Jürimäe (0000-0003-4819-5241, University of Tartu, corresponding author), Liina Remmel (0000-0001-9378-2125, University of Tartu), Anna‐Liisa Tamm (0000-0002-0425-2809, Tartu Health Care College), Priit Purge (0000-0003-2968-2220, University of Tartu), Katre Maasalu (University of Tartu), Vallo Tillmann (0000-0002-5279-4493, University of Tartu)
Year2023
Volume10
Issue7
Pages1226-1226
Publication date2023-07-14
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children10071226
PMID37508723
OpenAlexW4384525399
LanguageEN
Citations received1
References cited4

Follistatin is a member of the activin-follistatin-inhibin hormonal system and is proposed to affect bone metabolism. However, data regarding the effect of follistatin on bone are relatively scarce and contradictory in humans. The purpose of the current study was to investigate possible associations of serum follistatin concentration with bone mineral characteristics in lean and physically active adolescent girls. Bone mineral density, body composition, resting energy expenditure and different energy homeostasis hormones in serum including follistatin, leptin and insulin were investigated. Significant relationships ( p p 2 × 100; p = 0.049) of the total variance in LS aBMD values. In conclusion, serum follistatin concentrations were associated with bone mineral values in lean adolescent girls with increased physical activity. Follistatin was an independent predictor of lumbar spine areal bone mineral density, which predominantly consists of trabecular bone

Body weight · Bone density · Bone mineral · Follistatin · Lean body mass · Osteoporosis · Physical activity · Physical therapy · Body Composition Measurement Techniques · Bone health and osteoporosis research · Chemistry · Medicine · Nutrition and Health in Aging · Psychology · Endocrinology · Internal Medicine

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Unique citing works1
Citations per year0.5
Citation span2024 - 2024 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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