Epidemiology and Outcomes of Late-Onset Neonatal Sepsis in Preterm Infants in a Tertiary Hospital
Bibliographic Data
| ID | 15718455 |
|---|---|
| Authors | Katerina Kaffe (University of Thessaly, corresponding author), George A Syrogiannopoulos (0000-0002-2390-3603, University Hospital of Larissa), Efthimia Petinaki (University Hospital of Larissa), Maria Goudesidou (University of Thessaly), Anna Kalaitzi (University of Thessaly), Antonios Gounaris (University Hospital of Larissa), Ioanna N Grivea (0000-0002-9221-5628, University of Thessaly) |
| Year | 2025 |
| Volume | 12 |
| Issue | 5 |
| Pages | 532-532 |
| Publication date | 2025-04-22 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children12050532 |
| PMID | 40426711 |
| OpenAlex | W4409667126 |
| Language | EN |
| Citations received | 1 |
| References cited | 1 |
Background/Objective: Late-onset sepsis (LOS), a systemic infection occurring after 72 h of life, is a significant issue of morbidity and mortality in preterm neonates. Nevertheless, in this population, cultures frequently remain negative, even in the presence of typical clinical signs of sepsis. Materials and Methods: This single-center, retrospective study included preterm infants with a birth weight (BW) Results: Among 277 infants, 30 (10.8%) had CPLOS, 83 (30%) had CNLOS, and 164 (59.2%) had no sepsis. Significant differences were found between the groups regarding BW, GA, hospitalization duration, morbidity, and mortality ( p p p Conclusions: LOS, whether culture-proven or not, was associated with neonatal morbidity and mortality. CPLOS was linked to a worse prognosis, while CNLOS was also frequently diagnosed and associated with increased antibiotic use in Neonatal Intensive Care Units (NICUs)
Birth weight · Gestational age · Incidence (geometry · Klebsiella oxytoca · Klebsiella pneumoniae · Low birth weight · Mechanical ventilation · Mortality rate · Neonatal sepsis · Population · Pregnancy · Retrospective cohort study · Sepsis · Medicine · Neonatal and Maternal Infections · Sepsis Diagnosis and Treatment · Streptococcal Infections and Treatments · Epidemiology · Internal Medicine · Pediatrics
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |