Surgical Versus Non-Surgical Treatment of Patients with Myopathic Scoliosis
Clinical, Radiological and Functional Outcomes
Bibliographic Data
| ID | 15719339 |
|---|---|
| Authors | Alexandra Satanovsky (Hadassah Medical Center), Rana Hanna (0000-0003-2082-2872, Rambam Health Care Campus), Patrice L Weiss (0000-0001-5633-1210, Alyn Hospital), Amihai Rigbi (0000-0002-0048-2850, Beit Berl College), Josh E Schroeder (0000-0002-0238-6248, Hadassah Medical Center), Sharon Eylon (0000-0002-2614-8084, Hebrew University of Jerusalem, corresponding author) |
| Year | 2025 |
| Volume | 12 |
| Issue | 11 |
| Pages | 1562-1562 |
| Publication date | 2025-11-17 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children12111562 |
| PMID | 41300678 |
| OpenAlex | W4416404845 |
| Language | EN |
| References cited | 37 |
Background/Objectives: Myopathies are acquired or genetic muscle diseases causing weakness and wasting, leading to poor posture, impaired coordination, reduced daily function, and scoliosis. The objective of this ambispective study was to compare clinical, radiological, and functional outcomes of patients with myopathic scoliosis treated surgically or non-surgically. Methods: We identified 118 patients (55% male) with myopathy and scoliosis from ALYN Rehabilitation Hospital's database (1990-2022). Mean age at first visit was 5.45 ± 5.27 years. Seventeen (14%) underwent scoliosis surgery; others were managed non-surgically. Due to unbalanced group sizes, comparative group analyses used propensity score matching (15 surgical, 30 non-surgical patients). Retrospective data included demographics, medical history, respiratory and mobility status, Cobb angle (CA), pelvic obliquity (PO), and surgical details when applicable. Prospective telephone interviews were conducted including SRS-22r Quality of Life (QoL), WHO-QoL, and Functional Independence Measure for Children (WeeFIM). Results: Longitudinal analysis showed significant or near-significant worsening over time in CA ( p = 0.03) and PO ( p = 0.08), regardless of treatment type but no significant difference between surgical and non-surgical groups in progression rates. Interview data, for 7 surgical and 6 non-surgical patients, revealed that surgical patients reported higher overall QoL, FIM, and SRS-22r self-image scores, but lower scores for SRS-22r pain, general function, and activity levels. Conclusions: Existing research and this study suggest that despite surgical risks, scoliosis correction in neuromuscular conditions generally leads to improved QoL. Findings highlight the complexity of surgical decision-making for myopathic scoliosis, where medical risks must be weighed against potential long-term functional and QoL outcomes
Activities of daily living · Propensity score matching · Quality of life (healthcare · Radiological weapon · Retrospective cohort study · Scoliosis · Weakness · Hip disorders and treatments · Scoliosis diagnosis and treatment · Shoulder Injury and Treatment · Rehabilitation
| Citation velocity | historical |
|---|---|
| Highly cited | No |