Neurodevelopmental Outcome at 6 Months Following Neonatal Resuscitation in Rural Tanzania
Bibliographic Data
| ID | 15719462 |
|---|---|
| Authors | Ingrid Ask Torvik (0000-0001-6781-2722, University of Stavanger, corresponding author), Robert Moshiro (0000-0002-9036-0266, Muhimbili National Hospital), Hege Ersdal (0000-0002-2795-8564, Stavanger University Hospital), Anita Yeconia (Haydom Lutheran Hospital), Raphael Mduma (Haydom Lutheran Hospital), Jeffrey Perlman (Department of Pediatrics, Weill Cornell Medical College, New York, NY 10065, USA), Jeffrey M Perlman (0000-0002-9754-579X, Cornell University), Jørgen Linde (Stavanger University Hospital) |
| Year | 2023 |
| Volume | 10 |
| Issue | 6 |
| Pages | 957-957 |
| Publication date | 2023-05-27 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children10060957 |
| PMID | 37371189 |
| OpenAlex | W4378527857 |
| Language | EN |
| Citations received | 1 |
| References cited | 24 |
Early bag-mask ventilation (BMV) administered to non-breathing neonates at birth in the presence of birth asphyxia (interruption of placental blood flow) has reduced neonatal mortality by up to 50% in low- and middle-income countries. The neurodevelopmental outcome of neonates receiving BMV remains unknown. Using the Malawi Developmental Assessment Tool (MDAT), infants who received BMV at birth were assessed at 6 months, evaluating gross motor, fine motor, language and social skills. A healthy cohort with no birth complications was assessed with the same tool for comparison. Mean age-adjusted MDAT z-scores were not significantly different between the groups. The number of children having developmental delay defined as a z-score ≤ -2 was significantly higher in the resuscitated cohort for the fine motor and language domain and overall MDAT z-score. The prevalence of clinical seizures post discharge was significantly higher in the resuscitated group and was associated with neurodevelopmental delay. Infants with developmental delay or seizures were more likely to have a 5 min Apgar < 7 and a longer duration of BMV. Most children receiving BMV at birth are developing normally at 6 months. Still, there are some children with impaired development among resuscitated children, representing a subgroup of children who may have suffered more severe asphyxia
Anesthesia · Apgar score · Asphyxia · Birth weight · Cohort · Cohort study · Gross motor skill · Motor skill · Neonatal resuscitation · Pregnancy · Psychiatry · Resuscitation · Infant Development and Preterm Care · Medicine · Neonatal and fetal brain pathology · Neonatal Respiratory Health Research · Internal Medicine · Pediatrics
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |