The Role of the Pediatric Yorkhill Malnutrition Score (Pyms), Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Malnutrition Prediction of Hospitalized Children
Bibliographic Data
| ID | 15719689 |
|---|---|
| Authors | Spyridoula Gysi (University of Basel, corresponding author), Michael Doulberis (0000-0002-0396-5081, University of Zurich), Corinne Légeret (0000-0001-6972-542X, University of Basel), Henrik Köhler (0000-0002-3197-329X, University of Basel) |
| Year | 2022 |
| Volume | 9 |
| Issue | 9 |
| Pages | 1378-1378 |
| Publication date | 2022-09-13 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Children (JOURNAL) |
| Journal identifiers | ISSN: 2227-9067 • E-ISSN: 2227-9067 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/children9091378 |
| PMID | 36138687 |
| OpenAlex | W4295976266 |
| Language | EN |
| Citations received | 1 |
| References cited | 24 |
Malnutrition in hospitalized children represents a significant burden with occasionally detrimental consequences. In this retrospective analysis of pediatric patients aged one to 16 years old, who were hospitalized in the children’s cantonal hospital of Aarau, Switzerland, we investigated the utilization of PYMS (Pediatric Yorkhill Malnutrition Score) as a routine screening tool for malnutrition in pediatric inpatients. Additionally, we explored the correlation between PYMS and NLR (neutrophil−lymphocyte ratio) and PLR (platelet−lymphocyte ratio), which are two novel biomarkers. Various parameters were analyzed from the medical records of the patients. Most of the sample (n = 211, 77.3%) was characterized by a low PYMS of 0−1 point. Greater NLR and PLR values were significantly associated with greater PYMS (p = 0.030 and p = 0.004, respectively). ROC (receiver operating characteristic curves) analysis revealed that PLR had a significant predictive ability for having PYMS > 1 (AUC = 0.59; 95% CI: 0.51−0.68; p = 0.024). The optimal cut-off was 151 with sensitivity of 51.6% (95% CI: 38.6−64.5%) and specificity of 67.3% (95% CI: 60.5−73.6%). Furthermore, 37% of the children (n = 101) yielded a PLR over 151. Our results support a promising value of PLR as a predictive marker for moderate to severe malnutrition in hospitalized children
Lymphocyte · Malnutrition · Medical record · Platelet · Predictive value · Receiver operating characteristic · Child Nutrition and Water Access · Clinical Nutrition and Gastroenterology · Medicine · Nutrition and Health in Aging · Gastroenterology · Internal Medicine · Pediatrics
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |