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Long-Term Hepatitis B Vaccine Immunity in Ethiopian Children That Received a Pentavalent Vaccine Series

A Retrospective Cohort Study

Bibliographic Data

ID15719703
AuthorsTinsae Alemayehu (0000-0003-0699-8433, University of Botswana), Million Dechassa Daba (St. Paul's Hospital Millennium Medical College), Danilo Buonsenso (0000-0001-8567-2639, Agostino Gemelli University Polyclinic, corresponding author)
Year2024
Volume11
Issue1
Pages136-136
Publication date2024-01-22
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11010136
PMID38275446
OpenAlexW4391097918
LanguageEN

Our study showed markedly low vaccine-induced hepatitis B surface antibody levels among the study population, especially adolescents. The presence of breakthrough infections may suggest a genuine lack of response and not just a mere drop in antibody titers and thus could highlight a significant public health problem in Ethiopia. Further immunologic studies and a thorough analysis of vaccine storage and administration should be conducted to inform prevention programs

Antibody · Cohort · HBsAg · Hepatitis B · Hepatitis B vaccine · Hepatitis B virus · Retrospective cohort study · Serology · Transmission (telecommunications · Vaccination · Virus · Hepatitis B Virus Studies · Hepatitis Viruses Studies and Epidemiology · Liver Disease Diagnosis and Treatment · Medicine · Immunology · Internal Medicine · Pediatrics

Highly citedNo

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