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Preschool Language Development of Children Born to Women with an Opioid Use Disorder

Bibliographic Data

ID15719738
AuthorsHyun Min Kim (0000-0002-0138-0653, University of Canterbury, corresponding author), Reisha Bone (University of Canterbury), Reisha M Bone (University of Canterbury), Brigid McNeill (0000-0002-7298-880X, University of Canterbury), Samantha J Lee (0000-0002-0444-6283, University of Canterbury), Gail Gillon (0000-0001-9501-8147, University of Canterbury), Lianne J Woodward (0000-0002-7790-1435, University of Canterbury)
Year2021
Volume8
Issue4
Pages268-268
Publication date2021-03-31
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children8040268
PMID33807265
OpenAlexW3142313724
LanguageEN
Citations received2
References cited53

Increasing evidence suggests that prenatal exposure to opioids may affect brain development, but limited data exist on the effects of opioid-exposure on preschool language development. Our study aimed to characterize the nature and prevalence of language problems in children prenatally exposed to opioids, and the factors that support or hinder language acquisition. A sample of 100 children born to pregnant women in methadone maintenance treatment and 110 randomly identified non-exposed children were studied from birth to age 4.5 years. At 4.5 years, 89 opioid-exposed and 103 non-exposed children completed the preschool version of the Clinical Evaluation of Language Fundamentals (CELF-P) as part of a comprehensive neurodevelopmental assessment. Children prenatally exposed to opioids had poorer receptive and expressive language outcomes at age 4.5 years compared to non-opioid exposed children. After adjustment for child sex, maternal education, other pregnancy substance use, maternal pregnancy nutrition and prenatal depression, opioid exposure remained a significant independent predictor of children's total CELF-P language score. Examination of a range of potential intervening factors showed that a composite measure of the quality of parenting and home environment at age 18 months and early childhood education participation at 4.5 years were important positive mediators

Affect (linguistics · Depression (economics · Developmental psychology · Early childhood · Language development · Methadone · Opioid · Opioid use disorder · Pregnancy · Psychiatry · Clinical Psychology · Infant Development and Preterm Care · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Prenatal Substance Exposure Effects · Psychology · Internal Medicine · Pediatrics

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Citations per year0.5
Citation span2022 - 2023 (2)
Highly citedNo

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