Different Features of Cholera in Malnourished and Non-Malnourished Children

Analysis of 20 Years of Surveillance Data from a Large Diarrheal Disease Hospital in Urban Bangladesh

Bibliographic Data

ID15719841
AuthorsSharika Nuzhat (0000-0003-1057-9960, International Centre for Diarrhoeal Disease Research), Md Iqbal Hossain (0000-0002-6827-4505, International Centre for Diarrhoeal Disease Research), Nusrat Jahan Shaly (0000-0002-9400-4322, International Centre for Diarrhoeal Disease Research), Rafiqul Islam (0000-0003-0545-6595, International Centre for Diarrhoeal Disease Research), Soroar Hossain Khan (0000-0001-5121-4779, International Centre for Diarrhoeal Disease Research), Abu Syed Golam Faruque (0000-0001-8343-4653, International Centre for Diarrhoeal Disease Research), Pradip Kumar Bardhan (International Centre for Diarrhoeal Disease Research), Azharul Islam Khan (International Centre for Diarrhoeal Disease Research), Mohammod Jobayer Chisti (0000-0001-9958-3071, International Centre for Diarrhoeal Disease Research, corresponding author), Tahmeed Ahmed (0000-0002-4607-7439, International Centre for Diarrhoeal Disease Research)
Year2022
Volume9
Issue2
Pages137-137
Publication date2022-01-20
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children9020137
PMID35204858
OpenAlexW4206707974
LanguageEN
Citations received1
References cited8

Malnourished children are more prone to infectious diseases including severe diarrhea compared to non-malnourished children. However, data are scarce on differences in the presentation in such children. We aimed to identify clinical differentials among children with cholera with or without malnutrition. Data were extracted from the diarrheal disease surveillance system (DDSS) of Dhaka Hospital of International Centre for Diarrheal Disease Research, Bangladesh (icddr,b) from January 2001 to December 2020. Among children under five in DDSS, cholera positive (culture confirmed) malnourished children (WAZ, WL/HZ or L/HAZ ˂ -2) were considered as cases ( n = 920) and children with cholera but non-malnourished (WAZ, WL/HZ or L/HAZ ≥-2.00 to ≤+2.00) were controls ( n = 586). After adjusting for potential confounders such as maternal illiteracy, day labor fathers, maternal employment, slum dwelling, non-sanitary latrine use, use of untreated water, and history of cough, it was revealed that malnourished cholera children significantly more often presented in hospital during evening hours (6 p.m. to 12 mid-night) ( p p 24 h history of diarrheal duration ( p p p < 0.05). The study results underscore the importance of understanding of basic differences in the presentation of severity of cholera in malnourished children for prompt identification and subsequent management of these vulnerable children

Cholera · Diarrhea · Diarrheal disease · Environmental health · Functional illiteracy · Malnutrition · Under-five · Child Nutrition and Water Access · Medicine · Vibrio bacteria research studies · Viral gastroenteritis research and epidemiology · Internal Medicine · Pediatrics

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