Complete Transposition of the Great Arteries in the Pediatric Field

A Multimodality Imaging Approach

Bibliographic Data

ID15720114
AuthorsSara Moscatelli (0000-0002-7370-1057, Guy's and St Thomas' NHS Foundation Trust), Martina Avesani (0000-0003-4970-4562, University of Padua), Nunzia Borrelli (0000-0002-4283-7824, Ospedale Monaldi), Jolanda Sabatino (0000-0002-1661-5419, Magna Graecia University), Valeria Pergola (0000-0002-3317-7342, University of Padua), Isabella Leo (0000-0002-4774-0888, Magna Graecia University), Claudia Montanaro (0000-0001-8613-8139, Guy's and St Thomas' NHS Foundation Trust), Francesca Valeria Contini (University of Cagliari), Francesca Contini (Clinical Cardiology Unit, Department of Medical Sciences and Public Health, University Hospital of Cagliari, Strada Statale 554, Km 4.500, 09042 Monserrato, Italy), Gabriella Gaudieri (Ospedale Monaldi), Jessica Ielapi (0009-0009-8291-284X, Magna Graecia University), Raffaella Motta (0000-0002-1886-9826, University of Padua), Marco Alfonso Perrone (0000-0002-0511-2621, University of Rome Tor Vergata), Giovanni Di Salvo (0000-0002-0305-0113, University of Padua, corresponding author)
Year2024
Volume11
Issue6
Pages626-626
Publication date2024-05-23
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children11060626
PMID38929206
OpenAlexW4398251459
LanguageEN
Citations received1
References cited76

The complete transposition of the great arteries (C-TGA) is a congenital cardiac anomaly characterized by the reversal of the main arteries. Early detection and precise management are crucial for optimal outcomes. This review emphasizes the integral role of multimodal imaging, including fetal echocardiography, transthoracic echocardiography (TTE), cardiovascular magnetic resonance (CMR), and cardiac computed tomography (CCT) in the diagnosis, treatment planning, and long-term follow-up of C-TGA. Fetal echocardiography plays a pivotal role in prenatal detection, enabling early intervention strategies. Despite technological advances, the detection rate varies, highlighting the need for improved screening protocols. TTE remains the cornerstone for initial diagnosis, surgical preparation, and postoperative evaluation, providing essential information on cardiac anatomy, ventricular function, and the presence of associated defects. CMR and CCT offer additional value in C-TGA assessment. CMR, free from ionizing radiation, provides detailed anatomical and functional insights from fetal life into adulthood, becoming increasingly important in evaluating complex cardiac structures and post-surgical outcomes. CCT, with its high-resolution imaging, is indispensable in delineating coronary anatomy and vascular structures, particularly when CMR is contraindicated or inconclusive. This review advocates for a comprehensive imaging approach, integrating TTE, CMR, and CCT to enhance diagnostic accuracy, guide therapeutic interventions, and monitor postoperative conditions in C-TGA patients. Such a multimodal strategy is vital for advancing patient care and improving long-term prognoses in this complex congenital heart disease

Artery · Cardiac Imaging · Cardiology · Coronary arteries · Fetal echocardiography · Fetus · Great arteries · Heart disease · Magnetic resonance imaging · Pregnancy · Prenatal diagnosis · Radiology · Congenital Heart Disease Studies · Coronary Artery Anomalies · Fetal and Pediatric Neurological Disorders · Medicine · Internal Medicine

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