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Relationship between High Blood Pressure and Microalbuminuria in Children Aged 6–9 Years in a South African Population

Bibliographic Data

ID15720125
AuthorsEdna Ngoakoana Matjuda (Department of Human Biology, Faculty of Health Sciences, Walter Sisulu University PBX1, 5117 Mthatha, South Africa), Constance R Sewani-Rusike (0000-0002-3295-2933, Walter Sisulu University), Samuel Nkeh Chungag Anye (Walter Sisulu University), Godwill Azeh Engwa (0000-0002-0044-9890, Walter Sisulu University), Benedicta Ngwechi Nkeh-Chungag (Walter Sisulu University, corresponding author)
Year2020
Volume7
Issue9
Pages131-131
Publication date2020-09-07
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children7090131
PMID32906740
OpenAlexW3083976764
LanguageEN
References cited48

Though the association between high blood pressure and microalbuminuria is well established in adults, there is a paucity of information on microalbuminuria in children. This study investigated the relationship between high blood pressure and microalbuminuria in 6-9-year-old children. A cross-sectional study, which included 306 primary school children of age 6-9 years old from urban areas (n = 154) and rural areas (n = 152) of the Eastern Cape Province of South Africa, was conducted. Participants' anthropometric data were determined and systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were measured and converted to BP percentiles for age, sex and height. Creatinine and albumin concentrations were assayed in early morning midstream urine and the albumin to creatinine ratio (ACR) was calculated. There was a 42.8% prevalence of elevated blood pressure/high blood pressure (E-BP/H-BP) and a 10.1% prevalence of microalbuminuria. Among the 131 children with E-BP/H-BP, 17 had elevated ACR with a prevalence of 13.95%. SBP and HR increased with increasing range of ACR and, furthermore, SBP was significantly ( p R 2 = 0.42, adj R 2 = 0.039, B : 0.120, p = < 0.05). In conclusion, microalbuminuria was present in 6-9-year-old South African children of African Ancestry and a weak association was observed with SBP in children

Anthropometry · Blood pressure · Cardiology · Creatinine · Environmental health · Microalbuminuria · Morning · Population · Urine · Blood Pressure and Hypertension Studies · Cardiovascular Health and Disease Prevention · Medicine · Sodium Intake and Health · Endocrinology · Internal Medicine

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