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Changing Epidemiology of Acute Viral Respiratory Infections in Hospitalized Children

The Post-Lockdown Effect

Bibliographic Data

ID15720152
AuthorsMarco Maglione (0000-0001-8181-2219, Santobono Children's Hospital), Antonia Pascarella (0000-0002-6997-8950, Santobono Children's Hospital), Chiara Botti (0000-0002-2304-5303, Santobono Children's Hospital), Giuseppe Ricci (0000-0002-0871-7618, Santobono Children's Hospital), Fiorella Morelli (Santobono Children's Hospital), Fabiana Camelia (Santobono Children's Hospital), Alberto Micillo (0000-0003-0586-8522, Santobono Children's Hospital), Camilla Calì (0000-0002-7228-2399, Santobono Children's Hospital), Fabio Savoia (0000-0001-7132-0050, Santobono Children's Hospital), Vincenzo Tipo (0000-0001-8159-2359, Santobono Children's Hospital), Antonietta Giannattasio (0000-0002-0160-0177, Santobono Children's Hospital, corresponding author)
Year2022
Volume9
Issue8
Pages1242-1242
Publication date2022-08-17
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children9081242
PMID36010132
OpenAlexW4292260946
LanguageEN
Citations received1
References cited17

Several reports highlighted how public health measures aimed at limiting severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) circulation have likely contributed to reducing the circulation of other respiratory viruses, particularly during the first year of the COVID-19 pandemic. We evaluated the epidemiology of acute respiratory infections in a large cohort of hospitalized children during the third year of the pandemic (2021−2022). We retrospectively analyzed data from the health records of children (<14 years) hospitalized for acute respiratory infections between 1 July 2021 and 31 March 2022. A total of 1763 respiratory panels were collected. Overall, 1269 (72%) panels hadpositive results for at least one pathogen. Most positive panels (53.8%) belonged to patients aged 1−12 months. The most detected pathogen was respiratory syncytial virus (RSV) (57.8% of positive panels). The RSV peak occurred in November 2021. Nine hundred and forty-five (74.5%) panels were positive for one pathogen while three hundred and twenty-four (25.5%) showed multiple infections. Patients with multiple infections were significantly older than those with a single infection. The 2021−2022 peak of RSV infection in Italy occurred earlier than in the previous pre-pandemic seasons. A high number of children have been hospitalized because of acute viral infections also due to less aggressive viruses

Cohort · Coronavirus disease 2019 (COVID-19 · Disease · Infectious disease (medical specialty · Outbreak · Pandemic · Pathogen · Respiratory system · COVID-19 and healthcare impacts · Medicine · Respiratory Support and Mechanisms · Respiratory viral infections research · Epidemiology · Immunology · Internal Medicine · Pediatrics · Virology

  • Parapneumonic Effusion Versus Pulmonary Empyema in Children

    Open Access•Marta Improta, Francesca Morlino et al.•Children•2025

  • Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016

    Open Access•Christopher Troeger, Brigette F Blacker et al.•The Lancet Infectious Diseases•2018

  • Epidemiology, Microbiology and Severity of Bronchiolitis in the First Post-Lockdown Cold Season in Three Different Geographical Areas in Italy

    Open Access•Anna Camporesi, Rosa Morello et al.•Children•2022

  • Respiratory viruses dynamics and interactions

    Open Access•Gibran Horemheb-Rubio, Ralf Eggeling et al.•BMC Public Health•2022

  • A global panel database of pandemic policies (Oxford Covid-19 Government Response Tracker)

    Open Access•Thomas Hale, Noam Angrist et al.•Nature Human Behaviour•2021

Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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