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Cross-Sectional Analysis of IL-6, TNF-α, Adiponectin, Leptin, and Klotho Serum Levels in Relation to BMI Among Overweight and Obese Children Aged 10–14 in La Rioja, Spain

Bibliographic Data

ID15720180
AuthorsBeatriz Fernández-Vallejo (Hospital San Pedro, corresponding author), Francisco Jiménez Monteagudo (Departamento de Salud), Lourdes Romero (0000-0001-7893-5779, Center for Biomedical Research of La Rioja), Maria Isabel López Aznárez (Pediatría de Atención Primaria, Centro de Salud Guindalera, 26006 Logroño, Spain), Miguel Cobas (0000-0002-6920-6408), María del Carmen Romero Cobas (Medicina Familiar y Comunitaria, Centro de Salud Gonzalo de Berceo, 26006 Logroño, Spain), Laura Pérez-Martínez (Centro de Investigación Biomédica de La Rioja (CIBIR), 26006 Logroño, Spain), Laura Pérez‐Martínez (0000-0002-1384-024X, Center for Biomedical Research of La Rioja)
Year2025
Volume12
Issue1
Pages89-89
Publication date2025-01-14
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueChildren (JOURNAL)
Journal identifiersISSN: 2227-9067 • E-ISSN: 2227-9067
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/children12010089
PMID39857920
OpenAlexW4406360398
LanguageEN
References cited38

This study underscores leptin and the L/A ratio as potential biomarkers of metabolic dysregulation in childhood obesity, particularly in females. Longitudinal studies are needed to confirm these findings and assess the clinical utility of these biomarkers in pediatric obesity management

Abdominal obesity · Adiponectin · Anthropometry · Body mass index · Childhood obesity · Cross-sectional study · Insulin resistance · Leptin · Metabolic syndrome · Obesity · Overweight · Adipokines, Inflammation, and Metabolic Diseases · Medicine · Obesity, Physical Activity, Diet · Regulation of Appetite and Obesity · Endocrinology · Internal Medicine

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    Open Access•The GBD Obesity Collaborators•New England Journal of Medicine•2017

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  • Childhood obesity

    Open Access•AjeetSingh Bhadoria, Krushnapriya Sahoo et al.•Journal of Family Medicine and…•2015

  • The global childhood obesity epidemic and the association between socio-economic status and childhood obesity

    Youfa Wang, Hyunjung Lim•International Review of Psychiatry•2012

  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing

    Open Access•Makoto Kuro-o, Makoto Kuro‐o et al.•Nature•1997

  • Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013

    Open Access•Marie Ng, Tom Fleming et al.•The Lancet•2014

Citation velocityhistorical
Highly citedNo

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