Agricultural production
Assessment of the potential use of Cas9-mediated gene drive systems for agricultural pest control
Bibliographic Data
| ID | 15735844 |
|---|---|
| Authors | Maxwell J Scott (0000-0001-6536-4735, North Carolina State University, corresponding author), Fred Gould (0000-0001-8597-5306, North Carolina State University), Marcé D Lorenzen (0000-0003-2318-1388, North Carolina State University), Nathaniel Grubbs (0000-0002-3631-7427, North Carolina State University), Owain R Edwards (0000-0003-3861-7906, CSIRO Land and Water), David A O’Brochta (Institute for Bioscience and Biotechnology Research) |
| Year | 2017 |
| Volume | 5 |
| Issue | sup1 |
| Pages | S98-S120 |
| Publication date | 2017-12-11 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Responsible Innovation (JOURNAL) |
| Journal identifiers | ISSN: 2329-9037 • E-ISSN: 2329-9460 |
| Publisher | Taylor & Francis (PUBLISHER • GB) |
| DOI | 10.1080/23299460.2017.1410343 |
| OpenAlex | W2773135720 |
| Language | EN |
| Citations received | 7 |
| References cited | 95 |
To highlight how gene drives could be useful for control of agricultural insect pests, we selected species that are pests of animals (New World screwworm), plants (spotted wing Drosophila, diamondback moth, Bemisia tabaci whitefly), or stored grains (red flour beetle). With the exception of whitefly, routine methods for delivering DNA to the germline and selecting for genetically modified insects have been developed. The traditional approach in agriculture has been to suppress insect pest populations using insecticides and other farming practices. Similarly, we suggest the main use of gene drives in agriculture will be for population suppression through targeting essential genes. We provide examples of gene drives that target specific genes including female-essential genes. Further, we discuss issues related to containment in the laboratory and eventual field testing of strains harboring a Cas9-mediated gene drive system
Agriculture · Biology · Botany · CRISPR · Diamondback moth · Gene · Gene drive · Genetically modified organism · Larva · PEST analysis · Pest control · Population · Whitefly · CRISPR and Genetic Engineering · Insect behavior and control techniques · Insect Resistance and Genetics · Biotechnology · Ecology · Genetics
Gene Drives as Interventions into Nature
The value of existing regulatory frameworks for the environmental risk assessment of agricultural pest control using gene drives
Food for thought
Identifying and detecting potentially adverse ecological outcomes associated with the release of gene-drive modified organisms
Gene drives and the expanding horizon of governance
Opening up, closing down, or leaving ajar? How applications are used in engaging with publics about gene drive
Gene drives and the management of agricultural pests
| Unique citing works | 7 |
|---|---|
| Citations per year | 0,78 |
| Citation span | 2017 - 2023 (7) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 7 |